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Browsing by Author "Guerrero Gómez, David"
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PhD Thesis
Estudio de los mecanismos moleculares que median el efecto protector del glutatión reducido en el mantenimiento de la proteostasis celular
Guerrero Gómez, David (2022-02-25)El mantenimiento de la proteostasis es crucial para la supervivencia de todos los organismos, ya que asegura la funcionalidad ...
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Article
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB
Parra Millán, Raquel; Guerrero Gómez, David; Ayerbe Algaba, Rafael; Pachón Ibáñez, María Eugenia; Miranda Vizuete, Antonio; Pachón Díaz, Jerónimo; Smani, Younes (American Society for Microbiology, 2018-03-28)Acinetobacter baumannii is a significant human pathogen associated with hospital-acquired infections. While adhesion, an ...
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Article
Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation
Guerrero Gómez, David; Mora Lorca, José Antonio; Sáenz Narciso, Beatriz; Naranjo Galindo, Francisco José; Muñoz Lobato, Fernando; Parrado Fernández, Cristina; Goikolea, Julen; Cedazo Minguez, Ángel; Link, Christopher D.; Goder, Veit; Miranda Vizuete, Antonio (Springer Nature, 2019)In the presence of aggregation-prone proteins, the cytosol and endoplasmic reticulum (ER) undergo a dramatic shift in their ...
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Article
Redox-dependent and redox-independent functions of Caenorhabditis elegans thioredoxin 1
Sanzo-Machuca, Ángela; Monje Moreno, José Manuel; Casado-Navarro, Rafael; Karakuzu, Ozgur; Guerrero Gómez, David; Fierro-González, Juan Carlos; Swoboda, Peter; Muñoz, Manuel J.; Miranda Vizuete, Antonio (Elsevier, 2019-06)Thioredoxins (TRX) are traditionally considered as enzymes catalyzing redox reactions. However, redox-independent functions ...