Now showing items 1-14 of 14

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      A common signalosome for programmed cell death in humans and plants 

      Martínez Fábregas, Jonathan; Díaz Moreno, Irene; González Arzola, Katiuska; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la (Nature Publishing Group, 2014)
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      Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition 

      Elena-Real, Carlos A.; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Velázquez Campoy, Adrián; Orzáez, Mar; López Rivas, Abelardo; Gil Caballero, Sergio; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Nature Publishing Group, 2018)
      Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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      Cytochrome c1 exhibits two binding sites for cytochrome c in plants 

      Moreno Beltrán, José Blas; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Velázquez Campoy, Adrián; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2014)
      n plants, channeling of cytochrome c molecules between complexes III and IV has been purported to shuttle electrons within ...
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      Exploring protein phosphorylation by combining computational approaches and biochemical methods 

      Pérez Mejías, Gonzalo; Velázquez Cruz, Alejandro; Guerra Castellano, Alejandra; Baños Jaime, Blanca; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2020)
      Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a ...
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      Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c 

      González Arzola, Katiuska; Díaz Quintana, Antonio Jesús; Rivero Rodríguez, Francisco; Velázquez Campoy, Adrián; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Oxford University Press, 2017)
      Higher-order plants and mammals use similar mechanisms to repair and tolerate oxidative DNA damage. Most studies on the ...
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      Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c 

      Rivero Rodríguez, Francisco; Díaz Quintana, Antonio Jesús; Velázquez Cruz, Alejandro; González Arzola, Katiuska; Gavilán Dorronzoro, María de la Paz; Velázquez Campoy, Adrián; Ríos Sánchez, Rosa María; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2021)
      Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by ...
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      Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus 

      González Arzola, Katiuska; Guerra Castellano, Alejandra; Rivero Rodríguez, Francisco; Casado Combreras, Miguel Ángel; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Rosa Acosta, Miguel Ángel de la (Wiley-Blackwell, 2021)
      Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually ...
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      New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants 

      Martínez Fábregas, Jonathan; Díaz Moreno, Irene; González Arzola, Katiuska; Janocha, Simon; Navarro Carruesco, José Antonio; Hervás Morón, Manuel; Bernhardt, Rita; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la (American Society for Biochemistry and Molecular Biology, 2013)
      Programmed cell death is an event displayed by many different organisms along the evolutionary scale. In plants, programmed ...
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      Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria 

      Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Pérez Mejías, Gonzalo; Elena-Real, Carlos A.; González Arzola, Katiuska; García Mauriño, Sofía M.; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (National Academy of Sciences, 2018)
      Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective ...
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      PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ 

      Casado Combreras, Miguel Ángel; Rivero Rodríguez, Francisco; Elena-Real, Carlos A.; Molodenskiy, Dmitry; Díaz Quintana, Antonio Jesús; Martinho, Marlène; Gerbaud, Guillaume; González Arzola, Katiuska; Velázquez Campoy, Adrián; Svergun, Dmitri; Belle, Valérie; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Research Network of Computational and Structural Biotechnology, 2022)
      Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ...
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      Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength 

      Moreno Beltrán, José Blas; Díaz Moreno, Irene; González Arzola, Katiuska; Guerra Castellano, Alejandra; Velázquez Campoy, Adrián; Rosa Acosta, Miguel Ángel de la; Díaz Quintana, Antonio Jesús (Elsevier, 2015)
      The transient interactions of respiratory cytochrome c with complexes III and IV is herein investigated by using heterologous ...
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      Structural and Functional Analysis of Novel Human Cytochrome c Targets in Apoptosis 

      Martínez Fábregas, Jonathan; Díaz Moreno, Irene; González Arzola, Katiuska; Janocha, Simon; Navarro Carruesco, José Antonio; Hervás Morón, Manuel; Bernhardt, Rita; Velázquez Campoy, Adrián; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la (American Society for Biochemistry and Molecular Biology, 2014)
      Since the first description of apoptosis four decades ago, great efforts have been made to elucidate, both in vivo and in ...
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      Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c 

      González Arzola, Katiuska; Díaz Moreno, Irene; Cano González, Ana María; Díaz Quintana, Antonio Jesús; Velázquez Campoy, Adrián; Moreno Beltrán, José Blas; López Rivas, Abelardo; Rosa Acosta, Miguel Ángel de la (National Academy of Sciences, 2015)
      Chromatin is pivotal for regulation of the DNA damage process insofar as it influences access to DNA and serves as a DNA ...
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      Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 

      Moreno Beltrán, José Blas; Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Conte, Rebecca del; García Mauriño, Sofía M.; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (National Academy of Sciences, 2017)
      Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and ...