Now showing items 1-7 of 7

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      Caspase-8 inhibition represses initial human monocyte activation in septic shock model  [Article]

      Oliva Martín, María José; Sánchez Abarca, Luis Ignacio; Rodhe, Johanna; Carrillo Jiménez, Alejandro; Vlachos, Pinelopi; Herrera Carmona, Antonio José; García Quintanilla, Alberto; Caballero Velázquez, Teresa; Venero Recio, José Luis (Impact Journals, 2016)
      In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic potential of directly targeting innate immune cell activation to limit the cytokine storm and downstream ...
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      Deciphering GRINA/Lifeguard1: Nuclear Location, Ca2+ Homeostasis and Vesicle Transport  [Article]

      Jiménez González, Victor; Ogalla García, María Elena; García Quintanilla, Meritxell de Jesús; García Quintanilla, Alberto (MDPI, 2019)
      The Glutamate Receptor Ionotropic NMDA-Associated Protein 1 (GRINA) belongs to the Lifeguard family and is involved in calcium homeostasis, which governs key processes, such as cell survival or the release of neurotransmitters. ...
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      Inhibidores de la Caspasa 8  [Final Degree Work]

      Ocaña Campos, Rocío (2018-07)
      Esta revisión bibliográfica trata de explicar de forma sencilla qué son los inhibidores de la caspasa 8. Para ello se explicará en principio qué es la muerte celular, qué tipos de muerte celular se llevan a cabo en la ...
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      Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation  [Article]

      Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015)
      Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in microglia’s inflammatory response ...
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      Protease technology for obtaining a soy pulp extract enriched in bioactive compounds: isoflavones and peptides  [Article]

      Orts Gómez, Ángel; Revilla Torres, María Elisa; Rodríguez Morgado, Bruno; Castaño Navarro, Angélica; Tejada Moral, Manuel; García Quintanilla, Alberto (Elsevier: Creative Commons Licenses, 2019)
      This work presents a new bioprocess process for the extraction of bioactive components from soy pulp by-product (okara) using an enzymatic technology that was compared to a conventional water extraction. Okara is rich in ...
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      Relevance of chronic stress and the two faces of microglia in Parkinson’s disease  [Article]

      Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Carrillo Jiménez, Alejandro; Oliva Martín, María José; García Revilla, Juan; García Quintanilla, Alberto; Martínez de Pablos, Rocío; Venero Recio, José Luis (rontiers Research Foundation, 2015)
      This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the inflammatory response of brain microglia and hence its potential involvement in Parkinson’s ...
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      Spo0a: Más allá de la esporulación en Bacillus  [Final Degree Work]

      Rodríguez Lancharro, Marcos (2019)
      Cuando hablamos de supervivencia entre bacterias, uno de los mejores ejemplos es la bacteria del suelo Bacillus subtilis. Esta bacteria es capaz de hacer frente a situaciones extremas en cuanto a nutrientes y condiciones ...