Now showing items 1-8 of 8

    • Article
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      A quantitative principle to understand 3D cellular connectivity in epithelial tubes 

      Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Anbari, Samira; Tagua Jáñez, Antonio; Gordillo Vázquez, Carmen María; Palacios, Ana M.; Velasco, Antonio; Capitán Agudo, Carlos; Grima Ruiz, Clara Isabel; Robles Arias, Rafael; Márquez Pérez, Alberto; Buceta, Javier; Escudero Cuadrado, Luis María (BioRxiv, 2020)
      Apico-basal cell intercalations (scutoids) optimize packing and energy expenditure in curved epithelia. Further consequences ...
    • Article
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      Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia 

      Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio Jesús; Forja, Cristina; Castro Rodríguez, Ana María; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Research, 2018)
    • Article
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      EpiGraph: an open-source platform to quantify epithelial organization 

      Vicente Munuera, Pablo; Gómez Gálvez, Pedro; Tetley, Robert J.; Forja Barbosa, Cristina; Tagua Jáñez, Antonio Jesús; Letrán, Marta; Tozluoglu, Melda; Mao, Yanlan; Escudero Cuadrado, Luis María (Oxford University Press, 2020)
      Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational ...
    • Article
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      Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy 

      Piñol Jurado, Patricia; Suárez Calvet, Xavier; Fernández Simón, Esther; Gallardo, Eduard; Gómez Gálvez, Pedro; Escudero Cuadrado, Luis María; Díaz Manera, Jordi (Nature Publishing Group, 2018)
      Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin ...
    • Article
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      Non-productive angiogenesis disassembles Aß plaque-associated blood vessels 

      Álvarez Vergara, Maria I.; Rosales Nieves, Alicia E.; March Díaz, Rosana Rocío; Rodríguez Perinan, Guiomar; Lara Ureña, Nieves; Ortega de San Luis, Clara; Sánchez García, Manuel A.; Martín Bornez, Miguel; Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Fernández Gómez, Beatriz; Marchena, Miguel Ángel (Springer Nature, 2021)
      The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature ...
    • Article
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      Rules of tissue packing involving different cell types: human muscle organization 

      Sánchez Gutiérrez, Daniel; Sáez Manzano, Aurora; Gómez Gálvez, Pedro; Paradas López, Carmen ‎; Escudero Cuadrado, Luis María (Nature Publishing Group, 2017)
      Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial ...
    • Article
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      Scutoids are a geometrical solution to three-dimensional packing of epithelia 

      Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio; Forja Barbosa, Cristina; Castro Rodríguez, Ana María; Letrán, Marta; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Serrano Pérez-Higueras, Óscar; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Publishing Group, 2018)
      As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ...
    • PhD Thesis
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      Scutoids unveil the three-dimensional packing in curved epithelia 

      Gómez Gálvez, Pedro (2020-07-16)
      As animals develop, the initial simple planar epithelia of the early embryos must acquire complex three-dimensional ...