Now showing items 1-10 of 10

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      Acuaporinas en diversas patologías neurológicas  [PhD Thesis]

      Sánchez Gomar, Ismael (2016-06-17)
      El agua es un compuesto esencial para la vida. La mayoría de las moléculas (iones, azúcares, proteínas, etc.) que forman parte de los seres vivos se encuentran disueltos en medio acuoso. Para realizar sus funciones, las ...
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      AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis  [Article]

      Toledo Aral, Juan José; Echevarría Irusta, Miriam; Villadiego Luque, Francisco Javier (MDPI, 2019-02-24)
      Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) ...
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      Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders  [Article]

      Sánchez Gomar, Ismael; Díaz Sánchez, María; Uclés Sánchez, Antonio José; Casado Chocán, José Luis; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Villadiego Luque, Francisco Javier; Toledo Aral, Juan José; Echevarría Irusta, Miriam (MDPI AG, 2016-07-23)
      Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has improved diagnosis of these processes and differentiation from Multiple sclerosis (MS). Recent findings ...
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      Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α  [Article]

      Abreu Rodríguez, Irene; Sánchez Silva, Rocío; Martins, Ana Paula; Soveral, Graça; Toledo Aral, Juan José; López Barneo, José; Echevarría Irusta, Miriam (2011)
      Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported that this protein contributes to gas permeation (CO2, NO and O2) through the plasma membrane. We show ...
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      Neuroprotección en un nuevo modelo de animal transgénico  [PhD Thesis]

      Mejías Estévez, Rebeca María (2006-06-20)
      El objetivo general de este proyecto fue analizar en un modelo de parkinsonismo experimental en ratones, si el aumento del poder reductor de forma selectiva en las neuronas dopaminérgicas nigrostriatales (neuronas DNS9, ...
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      Overexpression of aquaporin-1 in lung adenocarcinomas and pleural mesotheliomas  [Article]

      López-Campos Bodineau, José Luis; Sánchez Silva, Rocío; Gómez Izquierdo, Lourdes; Márquez, Eduardo; Ortega Ruiz, Francisco; Cejudo Ramos, Pilar; Barrot Cortés, Emilia; Toledo Aral, Juan José; Echevarría Irusta, Miriam (2011-04-01)
      Aquaporin-1 (AQP1) is the main water channel responsible for water transport through many epithelia and endothelia. The latest evidence pointed toward an important role of this protein also in gas permeation, angiogenesis, ...
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      Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders  [Article]

      García Miranda, Pablo; Morón Civanto, Francisco Jesús; Martínez Olivo, María del Mar; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Lebrato-Hernández, Lucía; Lamas-Pérez, Lucía; Navarro, Gemma; Abril-Jaramillo, Javier; García Sánchez, María Isabel; Casado Chocán, José Luis; Uclés Sánchez, Antonio José; Romera, Mercedes; Echevarría Irusta, Miriam; Díaz Sánchez, María (MDPI, 2019-11-19)
      The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis. Recently, a group ...
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      Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1  [PhD Thesis]

      Muñoz Cabello, Ana María (2007-02-02)
      El desarrollo de esta Tesis se ha centrado en el estudio de los mecanismos celulares que permiten la quimiotransducción de O2 y CO2 en órganos como el cuerpo carotídeo y la médula adrenal. Teniendo en cuenta las evidencias ...
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      Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors  [Article]

      Muñoz Cabello, Ana María; Toledo Aral, Juan José; López Barneo, José; Echevarría Irusta, Miriam (2005)
      We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric recordings, we measured catecholamine (CAT) secretion from cells inAMslices of neonatal and adult ...
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      Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats  [Article]

      Toledo Aral, Juan José; Méndez Ferrer, Simón; Pardal Redondo, Ricardo; Echevarría Irusta, Miriam; López Barneo, José (2003)
      We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with carotid body (CB) cell aggregates. Amelioration of their motor syndrome is a result of the trophic ...