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Browsing by Author "Díez-Quijada Jiménez, Leticia"
Now showing items 1-20 of 24
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Article
A new method for the simultaneous determination of cyanotoxins (Microcystins and Cylindrospermopsin) in mussels using SPE-UPLC-MS/MS
Díez-Quijada Jiménez, Leticia; Guzmán Guillén, Remedios; Cătunescu, Giorgiana M.; Campos, Alexandre; Vasconcelos, Vitor; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2020)The aim of this study was to optimize the extraction conditions of Microcystin-LR (MC-LR), Microcystin-RR (MC-RR), ...
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Article
Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Llana Ruiz-Cabello, María; Cătunescu, Giorgiana M.; Moyano Salvago, Rosario; Risalde, María de los Angeles; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2020)Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and ...
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Article
Effect of cold food storage techniques on the contents of Microcystins and Cylindrospermopsin in leaves of spinach (Spinacia oleracea) and lettuce (Lactuca sativa)
Casas Rodríguez, Antonio; Díez-Quijada Jiménez, Leticia; Prieto Ortega, Ana Isabel; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2022-11-06)The presence of Cylindrospermopsin (CYN) and Microcystins (MCs) in vegetables is considered as a significant worldwide ...
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Final Degree Project
Evaluación de la genotoxicidad de un compuesto del extracto proallium ap® mediante el ensayo de micronucleos con potencial uso en envases alimentarios
Díez-Quijada Jiménez, Leticia (2016)Los aceites esenciales (AEs) que proceden del género Allium spp, como es el caso del ajo (Allium sativum) y la cebolla ...
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Article
Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
Díez-Quijada Jiménez, Leticia; Moyano, Rosario; Molina Hernández, Verónica; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Elsevier, 2021-05)Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans ...
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Article
Genotoxic Effects of Cylindrospermopsin, Microcystin-LR and Their Binary Mixture in Human Hepatocellular Carcinoma (HepG2) Cell Line
Díez-Quijada Jiménez, Leticia; Hercog, Klara; Štampar, Martina; Filipič, Metka; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía; Žegura, Bojana (MDPI, 2020)Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in the aquatic environment ...
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Article
Genotoxicity Evaluation of Propyl-Propane-Thiosulfinate (PTS) from Allium genus Essential Oils by a Combination of Micronucleus and Comet Assays in Rats
Cascajosa Lira, Antonio; Puerto Rodríguez, María; Prieto Ortega, Ana Isabel; Pichardo Sánchez, Silvia; Díez-Quijada Jiménez, Leticia; Baños, Alberto; Gillamón, Enrique; Moyano, Rosario; Molina Hernández, Verónica; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Multidisciplinary Digital Publishing Institute (MDPI), 2021)Propyl-propanethiosulfinate (PTS) is a component of Allium essential oils. This organosulfur molecule can be used as a ...
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Article
Immunomodulatory Effects of Pure Cylindrospermopsin in Rats Orally Exposed for 28 Days
Díez-Quijada Jiménez, Leticia; Casas Rodríguez, Antonio; Guzmán Guillén, Remedios; Molina Hernández, Verónica; González Albaladejo, Rafael; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has been classified as a ...
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Article
Immunotoxic Effects Induced by Microcystins and Cylindrospermopsin: A Review
Díez-Quijada Jiménez, Leticia; Benítez González, María del Monte; Puerto Rodríguez, María; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (MDPI, 2021)Cyanotoxin occurrence is gaining importance due to anthropogenic activities, climate change and eutrophication. Among them, ...
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Article
Impact of Gastrointestinal Digestion In Vitro Procedure on the Characterization and Cytotoxicity of Reduced Graphene Oxide
Cebadero Domínguez, Óscar; Díez-Quijada Jiménez, Leticia; López Martín, Sergio; Sánchez Ballester, Soraya; Puerto Rodríguez, María; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2023)The growing interest in graphene derivatives is a result of their variety of applications in many fields. Due to their ...
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PhD Thesis
Implicaciones en seguridad alimentaria derivadas de la exposición a cilindrospermopsina y microcistinas: evaluación toxicológica
Díez-Quijada Jiménez, Leticia (2021-04-20)En la actualidad, como consecuencia del cambio climático, la eutrofización de las aguas y el desarrollo de actividades ...
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Chapter of Book
La importancia de la Toxicología: aplicación de un Ciclo de Mejora en prácticas de Toxicología de la asignatura Laboratorio de Farmacia
Díez-Quijada Jiménez, Leticia (Universidad de Sevilla, 2023)En el segundo cuatrimestre del curso académico 2022/2023 se ha llevado a cabo la aplicación de un Ciclo de Mejora en el ...
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Article
In vitro assessment of cyanotoxins bioaccessibility in raw and cooked mussels
Díez-Quijada Jiménez, Leticia; Guzmán Guillén, Remedios; Cascajosa Lira, Antonio; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2020)The oral route by ingestion of water and food contaminated with cyanotoxins is the main route of exposure to these toxins. ...
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Article
In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin
Díez-Quijada Jiménez, Leticia; Prieto Ortega, Ana Isabel; Puerto Rodríguez, María; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (MDPI, 2019)The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for ...
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Article
In Vitro Mutagenic and Genotoxic Assessment of Anatoxin-a Alone and in Combination with Cylindrospermopsin
Plata Calzado, Cristina; Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (MDPI, 2023)Anatoxin-a (ATX-a) is a cyanobacterial toxin whose occurrence has been reported worldwide and has attracted increasing ...
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Article
In Vitro Toxicity Evaluation of Cyanotoxins Cylindrospermopsin and Microcystin-LR on Human Kidney HEK293 Cells
Díez-Quijada Jiménez, Leticia; Puerto Rodríguez, María; Gutiérrez-Praena, Daniel; Turkina, Maria V.; Campos, Alexandre; Vasconcelos, Vitor; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (MDPI, 2022-06)Cyanotoxins are secondary metabolites produced by different types of cyanobacteria. Among them, Cylindrospermopsin (CYN) ...
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Article
In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
Díez-Quijada Jiménez, Leticia; Llana Ruiz-Cabello, María; Catunescu, Giorgiana M.; Puerto Rodríguez, María; Moyano, Rosario; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2019)Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential ...
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Article
Influence of refrigeration and freezing in Microcystins and Cylindrospermopsin concentrations on fish muscle of tilapia (Oreochromis niloticus) and tench (Tinca tinca)
Díez-Quijada Jiménez, Leticia; Prieto Ortega, Ana Isabel; Guzmán Guillén, Remedios; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Elsevier, 2021)The consumption of fish contaminated with cyanotoxins is an important public health issue due to their potential adverse ...
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Article
Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad
Guzmán Guillén, Remedios; Puerto Rodríguez, María; Pichardo Sánchez, Silvia; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María; Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Cascajosa Lira, Antonio; Cebadero Domínguez, Óscar; Casas Rodríguez, Antonio; Plata Calzado, Cristina; Prieto Ortega, Ana Isabel (Real e Ilustre Colegio Oficial de Farmacéuticos de Sevilla, 2023)Las “Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias ...
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Final Degree Project
Modelos avanzados para el estudio de la toxicidad in vitro y su aplicación a cianotoxinas
Recio Remón, María de las Mercedes (2022)Las cianotoxinas son toxinas producidas por diferentes especies de cianobacterias, cuya proliferación está aumentando en ...