Browsing by Author "Cruz García, Andrés"
Now showing items 1-5 of 5
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Article
BRCA1 Accelerates CtIP-Mediated DNA-End Resection
(Elsevier, 2014)DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In ...
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PhD Thesis
Control de la procesividad de la resección por las proteinas CTIP, BRCA1 y las topoisomerasas del tipo II
(2017-01-16)Las cadenas de ADN pueden sufrir roturas debido a la acción de agentes exógenos, principalmente mutágenos químicos o ...
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Article
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
(Oxford University Press, 2015)DNA double strand breaks are the most cytotoxic lesions that can occur on the DNA. They can be repaired by different ...
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Article
Speed matters: How subtle changes in DNA end resection rate affect repair
(Taylor & Francis, 2015)The contribution of BRCA1 (breast cancer 1) to the repair of broken DNA is well established, but its real role at the ...
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Article
The COP9 signalosome is vital for timely repair of DNA double-strand breaks
(Oxford University Press, 2015)The DNA damage response is vigorously activated by DNA double-strand breaks (DSBs). The chief mobilizer of the DSB response ...