Browsing by Author "Cordero Morales, Mario David"
Now showing items 1-17 of 17
- Article
-
PhD Thesis
Autophagy dysfunctions and lysosomal permeabilization in Tay-Sachs and Sandhoff diseases
(2020-11-20)Autophagy is an essential intracellular process involved in survival, differentiation, development and cellular homeostasis. ...
- Article
-
Article
Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
(Public Library of Science, 2011)Background: We examined lipid peroxidation (LPO) in blood mononuclear cells (BMCs) and plasma, as a marker of oxidative ...
-
Article
Could NLRP3–inflammasome be a cardiovascular risk biomarker in acute myocardial infarction patients?
(2017)Conventional cardiovascular risk factors (CVRFs) are accepted to identify asymptomatic individuals with high risk of acute ...
-
Article
Current experience in testing mitochondrial nutrients in disorders featuring oxidative stress and mitochondrial dysfunction: rational design of chemoprevention trials
(MDPI AG, 2014-11-05)An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, ...
-
PhD Thesis
Implicación de la mitocondria y del complejo NLRP3-inflamasoma en la fisiopatología de la fibromialgia
(2015-12-11)La fibromialgia (FM) es un síndrome de dolor crónico generalizado de alta prevalencia mundial que supone un verdadero ...
-
PhD Thesis
Influencia de los parámetros mitocondriales en el agradamiento gingival inducido por ciclosporina y nifedipina: ensayo sobre modelo animal
(2016-07-15)El agrandamiento gingival es una entidad patológica englobada dentro de la clasificación de la enfermedad periodontal. Las ...
-
Article
Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria
(WILEY-BLACKWELL, 2021)Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). ...
-
Article
Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis
(Elsevier Science, 2011)Oxidative stress is one of the factors that could explain the pathophysiological mechanism of inflammatory conditions that ...
-
Patent. Invention
Modelo de roedor para fibromialgia y dolor crónico
(Oficina Española de Patentes y Marcas (OEPM), 2015-09-22)El objeto de la presente invención se refiere a un modelo de roedor para fibromialgia y dolor crónico, inducido por ...
-
Article
Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q10 Effect on Clinical Improvement
(Public Library of Science, 2012)Background: Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology and a wide spectrum of symptoms such as ...
- PhD Thesis
-
Article
Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
(Nature Publishing Group, 2015)Gaucher disease (GD) is caused by mutations in the GBA1 gene, which encodes lysosomal β-glucocerebrosidase. Homozygosity ...
-
PhD Thesis
Role of NLRP3-inflammasone in functional decline in physiological aging. Implications for cardio-metabolic events.
(2018-09-12)Aging constitutes the major risk factor for metabolic disabilities onset and cardiovascular disease. Clinically, is ...
-
Patent
Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.
(Oficina Española de Patentes y Marcas , 2011-08-02)Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.Composición farmacéutica que comprende ...
-
Patent
Uso de la metformina y derivados con actividad como inductores de la fosforilación de AMPK para el tratamiento de la fibromialgia
(Oficina Española de Patentes y Marcas , 2015-09-29)La presente invención tiene por objeto el uso de la metformina, derivados de la metformina y compuestos que contengan ...