Browsing by Author "Carmona Asenjo, Ana Teresa"
Now showing items 1-16 of 16
-
Article
Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry
(American Chemical Society, 2018)The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in ...
-
Article
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars
(Elsevier, 2022)Two libraries of mono- and dimeric pyrrolidine iminosugars were synthesized by CuAAC and (thio)urea-bond-forming reactions ...
- PhD Thesis
-
Article
Host-guest interactions between cyclodextrins and surfactants with functional groups at the end of the hydrophobic tail
(Elsevier, 2017)The aim of this work was to investigate the influence of the incorporation of substituents at the end of the hydrophobic ...
-
Article
Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds
(Schweizerische Chemische Gesellschaft, 2011)We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.
-
PhD Thesis
Preparación, aplicaciones y reactividad de nuevos derivados de iminoazúcares. Síntesis de análogos del FK866 con propiedades anticáncer
(2017-05-23)En esta Tesis Doctoral se ha desarrollado la síntesis de nuevos (pirrolidín-2-il)-Ctriazoles con configuración L-fuco ...
-
PhD Thesis
Reacciones Clic y evaluación in situ para la identificación de inhibidores de glicosidasas
(2021-07-16)Los iminoazúcares constituyen la categoría más importante de inhibidores de glicosidasas, sin embargo, su escasa selectividad ...
-
PhD Thesis
Síntesis estereoselectiva de nuevos furil-aminoácidos y su uso en la preparación de plataformas moleculares y de ligando de biomoléculas
(2009-03-27)Los polihidroxialquil-heterociclos son intermedios sintéticos muy interesantes para la preparación de productos de interés ...
-
Article
Stereoselective synthesis of chiral furan amino acid analogues of D- and L-serine from D-sugars
(Georg Thieme Verlag, 2006)The synthesis of chiral furan amino acid analogues of D - and L -serine is reported. The developed methodology ...
-
Article
Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.
-
Article
Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers
(Thieme Publishing; Georg Thieme Verlag, 2011)Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for ...
-
Article
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives
(Arkat USA, 2014)A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for ...
-
Article
Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases
(2010)The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of ...
-
Article
Synthesis of tri- and tetramines containing two 2,3-dihydroxypyrrolidine moieties and their inhibitory activity toward α-mannosidases
(Arkat USA, 2002)Through the reductive amination of N-[(tert-butoxy)carbonyl]-2,5-dideoxy-2, 5-imino-3,4-O-isopropylidene-L-ribose with ...
-
Article
Synthesis of tri- and tetramines containing two 2,3-dihydroxypyrrolidine moieties and their inhibitory activity toward α-mannosidases
(ARKAT USA INC, 2002)Through the reductive amination of N-[(tert-butoxy)carbonyl]-2,5-dideoxy-2,5-imino-3,4-Oisopropylidene-L-ribose with ...
-
Article
Total asymmetric synthesis of monosaccharides and analogues
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid ...
