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Browsing by Author "Begley, Victoria Sarah"
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Article
Asymmetric cell division requires specific mechanisms for adjusting global transcription
Mena, Adriana; Medina, Daniel A.; García Martínez, José Luis; Begley, Victoria Sarah; Singh, Abhyudai; Chávez de Diego, Sebastián; Muñoz Centeno, María de la Cruz; Pérez Ortín, José Enrique (Oxford University Press, 2017)Most cells divide symmetrically into two approximately identical cells. There are many examples, however, of asymmetric ...
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Article
Regulation of transcription elongation in response to osmostress
Silva, Andrea; Cavero, Santiago; Begley, Victoria Sarah; Solé, Carme; Böttcher, René; Chávez de Diego, Sebastián; Posas, Francesc; Nadal, Eulàlia de (Public Library of Science, 2017)Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase ...
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Article
The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4
Begley, Victoria Sarah; Corzo García, Daniel; Jordán Pla, Antonio; Cuevas Bermúdez, Abel; Miguel Jiménez, María Dolores De; Pérez Aguado, David; Machuca Ostos, Mercedes; Navarro Gómez, Francisco; Chávez de Diego, María José; Pérez Ortín, José Enrique; Chávez de Diego, Sebastián (Oxford University Press, 2019-10-10)Co-transcriptional imprinting of mRNA by Rpb4 and Rpb7 subunits of RNA polymerase II (RNAPII) and by the Ccr4–Not complex ...
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Article
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation
Gómez Herreros, Fernando; Margaritis, Thanasis; Rodríguez Galán, Olga; Pelechano, Vicent; Begley, Victoria Sarah; Millán Zambrano, Gonzalo; Morillo Huesca, Macarena; Muñoz Centeno, María de la Cruz; Pérez Ortín, José Enrique; Cruz Díaz, Jesús de la; Holstege, Frank C.P.; Chávez de Diego, Sebastián (Oxford University Press, 2017)Ribosome assembly requires the concerted expression of hundreds of genes, which are transcribed by all three nuclear RNA ...
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PhD Thesis
The role of RNA Polymerase II-dependent transcription elongation in the cross-talk between mRNA synthesis and decay.
Begley, Victoria Sarah (2018-02-06)The main molecule in gene expression is messenger RNA (mRNA) which transfers the information contained in genes in the ...
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Article
Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
Begley, Victoria Sarah; Jordán Pla, Antonio; Peñate Salas, Xenia; Garrido Godino, Ana Isabel; Challal, Drice; Cuevas Bermúdez, Abel; Mitjavila, Adrià; Barucco, Mara; Gutiérrez Pozo, Gabriel; Singh, Abhyudai; Alepuz, Paula M.; Chávez de Diego, Sebastián (Taylor & Francis, 2021)mRNA homoeostasis is favoured by crosstalk between transcription and degradation machineries. Both the Ccr4-Not and the ...