Now showing items 1-16 of 16

    • Article
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      A Role for Lipids in Protein Sorting? 

      Aguilera Romero, María Auxiliadora; Muñiz Guinea, Manuel (Swiss Chemical Society, 2021)
      Lipid and protein diversity provides structural and functional identity to the membrane compartments that define the ...
    • PhD Thesis
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      Análisis funcional del complejo p24 en Saccharomyces cerevisiae 

      Aguilera Romero, María Auxiliadora (2010)
      El propósito general de esta tesis es el análisis molecular de la función del complejo p24 en los procesos selectivos de ...
    • Article
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      Assay for dual cargo sorting into endoplasmic reticulum exit sites imaged by 3D Super-resolution Confocal Live Imaging Microscopy (SCLIM) 

      Rodríguez Gallardo, Sofía; Kurokawa, Kazuo; Cortés Gómez, Alejandro; Pérez Linero, Ana María; Aguilera Romero, María Auxiliadora; López, Sergio; Nakano, Akihiko (Public Library of Science, 2021)
      Understanding how in eukaryotic cells thousands of proteins are sorted from each other through the secretory pathway and ...
    • Article
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      Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites 

      Rodríguez Gallardo, Sofía; Kurokawa, Kazuo; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Ikeda, Atsuko; Zoni, Valeria; Aguilera Romero, María Auxiliadora; Pérez Linero, Ana María; López Martín, Sergio; Muñiz Guinea, Manuel (American Association for the Advancement of Science, 2020)
      Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition ...
    • Article
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      Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway 

      Manzano López, Javier; Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Pérez Linero, Ana María; Cordones Romero, Antonio; Aguilera Romero, María Auxiliadora; Lucena Hernández, Rafael; Muñiz Guinea, Manuel (Public Library of Science, 2022)
      Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and ...
    • Final Degree Project
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      Daltonismo y sus dificultades académicas 

      Silva Boceta, Alberto (2021)
      El daltonismo es una enfermedad visual que provoca dificultades académicas en la etapa de educación infantil y en los ...
    • Article
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      Determination of the lipid composition of the GPI anchor 

      Aguilera Romero, María Auxiliadora; Sabido Bozo, Susana; López Martín, Sergio; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Pérez Linero, Ana María; Riezman, Isabelle; Riezman, Howard; Muñiz Guinea, Manuel (PLOS, 2021)
      In eukaryotic cells, a subset of cell surface proteins is attached by the glycolipid glycosylphosphatidylinositol (GPI) ...
    • Article
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      Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum 

      López Martín, Sergio; Pérez Linero, Ana María; Manzano López, Javier; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Goder, Veit; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
      The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic ...
    • Article
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      Limited ER quality control for GPI-anchored proteins 

      Sikorska, Natalia; Lemus Rodríguez,Leticia; Aguilera Romero, María Auxiliadora; Manzano López, Miguel A.; Muñiz Guinea, Manuel; Goder, Veit (Rockefeller University Press, 2016)
      Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation ...
    • Article
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      Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast 

      Kajiwara, Kentaro; Ikeda, Atsuko; Aguilera Romero, María Auxiliadora; Castillon, Guillaume Alain; Kagiwada, Satoshi; Muñiz Guinea, Manuel; Funato, Kouichi (Company of Biologists Ltd, 2014)
      Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ...
    • Article
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      Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites 

      Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Ikeda, Atsuko; Araki, Misako; Okazaki, Kouta; Nakano, Miyako; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Waga, Miho; Nakano, Akihiko; Kurokawa, Kazuo; Muñiz Guinea, Manuel; Funato, Kouichi (Elsevier, 2022)
      Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export ...
    • Article
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      Structural analysis of the GPI glycan 

      Nakano, Miyako; Sabido Bozo, Susana; Okazaki, Kouta; Aguilera Romero, María Auxiliadora; Rodríguez Gallardo, Sofía; Cortés Gómez, Alejandro; López Martín, Sergio; Ikeda, Atsuko; Funato, Kouichi; Muñiz Guinea, Manuel (PLOS, 2021)
      Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes ...
    • Article
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      The ceramide synthase subunit lac1 regulates cell growth and size in fission yeast 

      Flor Parra, Ignacio; Sabido Bozo, Susana; Ikeda, Atsuko; Hanaoka, Kazuki; Aguilera Romero, María Auxiliadora; Funato, Kouichi; Muñiz Guinea, Manuel; Lucena Hernández, Rafael (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
      Cell division produces two viable cells of a defined size. Thus, all cells require mechanisms to measure growth and trigger ...
    • Article
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      The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection 

      Sabido Bozo, Susana; Pérez Linero, Ana María; Manzano López, Javier; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Wellinger, Ralf Erik; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
      Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ...
    • Article
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      The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus 

      Aguilera Romero, María Auxiliadora; Kaminska, Joanna; Spang, Anne; Riezman, Howard; Muñiz Guinea, Manuel (Rockefeller University Press, 2008)
      The p24 family members are transmembrane proteins assembled into heteromeric complexes that continuously cycle between the ...
    • Article
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      The yeast p24 complex regulates gpi-anchored protein Transport and quality control by monitoring anchor remodeling 

      Castillon, Guillaume Alain; Aguilera Romero, María Auxiliadora; Manzano López, Javier; Epsteina, Sharon; Kajiwarac, Kentaro; Funato, Kouichi; Watanabe, Reika; Riezman, Howard; Muñiz Guinea, Manuel (American Society for Cell Biology, 2011)
      Glycosylphosphatidylinositol (GPI)-anchored proteins are secretory proteins that are attached to the cell surface of ...