Browsing by Author "Álava Casado, Enrique de"
Now showing items 1-11 of 11
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Article
Breakthrough Technologies Reshape the Ewing Sarcoma Molecular Landscape
(MDPI, 2020)Ewing sarcoma is a highly aggressive round cell mesenchymal neoplasm, most often occurring in children and young adults. ...
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Article
Ciclos de mejora docente integrados en Anatomía Patológica: ¿primer paso hacia una enseñanza integrada?
(Universidad de Sevilla, 2018)Nuestra hipótesis es que el aprendizaje de los alumnos mejoraría si se integrasen contenidos de diversas asignaturas y ...
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PhD Thesis
Endoglin in Ewing sarcoma: from the biological relevance to a clinical strategy
(2021-06-11)Endoglin (ENG) is a mesenchymal stem cell (MSC) marker highly expressed mainly in active endothelium and certain cancer ...
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Article
Endoglin in the spotlight to treat cáncer
(MDPI, 2021-03-20)A spotlight has been shone on endoglin in recent years due to that fact of its potential to serve as both a reliable disease ...
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PhD Thesis
Estudio de los coactivadores transcripcionales TAZ y YAP1 en el sarcoma de Ewing: Implicación en la progresión tumoral e interacción funcional con la proteína de fusión EWS-FLI1
(2019-10-02)La presente tesis doctoral aborda, por primera vez, el papel funcional de los dos efectores finales de la vía Hippo, TAZ ...
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Article
HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients
(Impact Journals, 2017)Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT ...
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Article
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
(Impact Journals, 2017)Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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Article
Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study
(BMC, 2016-06-29)Background: Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST with KIT exon 9, PDGFRA mutation or ...
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Article
RING1B contributes to Ewing sarcoma development by repressing the Na(V)1.6 sodium channel and the NF-kappa B pathway, independently of the fusion oncoprotein
(Impact Journals, 2016-06-15)Ewing sarcoma (ES) is an aggressive tumor defined by EWSR1 gene fusions that behave as an oncogene. Here we demonstrate ...
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Article
Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma
(Springer Nature, 2021)Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver ...
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Article
The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease
(Impact Journals LLC, 2016-01-18)Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European ...