Estomatología

URI permanente para esta comunidadhttps://hdl.handle.net/11441/11014

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2-years retrospective observational case-control study on survival and marginal bone loss of implants in patients with hereditary coagulopathies
(Medicina oral S.L, 2023) Pérez Fierro, Manuel Luis; Castellanos Cosano, Lizett; Hueto-Madrid, Juan Antonio; López Jiménez, Julián; Núñez Vázquez, Ramiro José; Machuca-Portillo, Guillermo; Universidad de Sevilla. Departamento de Estomatología; Instituto de Biomedicina de Sevilla (IBIS)
Background: Evaluating 2-years implant loss and marginal bone loss in patients with hereditary coagulopathies, comparing with a healthy control group. Material and Methods: 37 implants in 13 patients (17 haemophilia A, 20 Von-Willebrand disease) versus 26 im plants in 13 healthy patients. Data measured through Lagervall-Jansson index (after surgery, at prosthetic loading, at 2 years). Statistics: Chi-square, Haberman’s, ANOVA, Mann-Whitney-U. Significance p<0.05. Results: Haemorrhagic accidents in 2 coagulopathies patients (non-statistical differences). Hereditary coagulopa thies patients suffered more hepatitis (p<0.05), HIV (p<0.05) and less previous periodontitis (p<0.01). Non-sta tistical differences in marginal bone loss among groups. 2 implants were lost in the hereditary coagulopathies and none in the control group (non-statistical differences). Hereditary coagulopathies patients had longer (p<0.001), and narrower implants (p<0.05) placed. 43.2% external prosthetic connection in hereditary coagulopathies pa tients (p<0.001); change of prosthetic platform more frequent in control group (p<0.05). 2 implants lost: external connection (p<0.05). Survival rate 96.8% (hereditary coagulopathies 94.6%, control group 100%). Conclusions: Implant and marginal bone loss at 2 years is similar in patients with hereditary coagulopathies and control group. Precautions should be taken on the treatment for hereditary coagulopathies patients, through prior haematological protocol. Implant loss only occurred in in a patient with Von-Willebrand´s disease.
A Comparison of Photoelastic and Finite Elements Analysis in Internal Connection and Bone Level Dental Implants
(2020-05-18) Herráez Galindo, Cristina; Torres-Lagares, Daniel; Martínez-González, Álvaro-José; Pérez-Velasco, Andrea; Torres Carranza, Eusebio; Serrera Figallo, María de los Ángeles; Gutiérrez Pérez, José Luis; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla. CTS523: Innovacion y Desarrollo en Tecnicas y Fundamentos de Cirugia Bucal y Craneofacial; Universidad de Sevilla. CTS1000: Odontología en Pacientes Especiales, Médicamente Comprometidos y Hospitalaria
This study is a contribution to our understanding of the mechanical behaviour of dental implants through the use of the finite element and the photoelastic methods. Two internal connection and bone level dental implants with different design have been analysed (M-12 by Oxtein S.L., Zaragoza, Spain, and ASTRA, from Dentsply Sirona, Charlotte, NC, USA), evaluating the stress distribution produced by axial stresses and a comparison has been established between them, as well as between the two methods used, in order to validate the adopted hypotheses and correlate the numerical modelling performed with experimental tests. To load the implant in laboratory testing, a column was placed, such that the loading point was about 9.3 mm from the upper free surface of the resin plate. This column connects the implant with the weights used to define the test load. In turn, support for both plates was achieved by two 6 mm bolts 130 mm apart and located on a parallel line with the resin (flush with the maximum level of the implant), at a depth of 90 mm. The results obtained with both methods used were similar enough. The comparison of results is fundamentally visual, but ensures that, at least in the range of forces used, both methods are similar. Therefore, the photoelastic method can be used to confirm in a real way the virtual conditions of the finite element models, with the implications in the investigation of dental implants that this entails.
A comparison of the dental status and treatment needs of older adults with and without chronic mental illness in Sevilla, Spain
(Medicina Oral S.L., 2012-06-07) Velasco-Ortega, Eugenio; Segura Egea, Juan José; Córdoba Arenas, Sara; Jiménez Guerra, Álvaro; Monsalve Guil, Loreto; López López, José; Universidad de Sevilla. Departamento de Estomatología
Objectives: To study the dental status and treatment needs of institutionalized older adults with chronic mental illness compared to a non-psychiatric control sample. Study Design: The sample size was 100, in which 50 were psychogeriatric patients (study group; SG) classified according to DSM-IV, with a mean age of 69.6 ± 6.7 years, and 50 non-psychiatric patients (control group; CG), with a mean age of 68.3 ± 6.9 years. Clinical oral health examinations were conducted and caries were recorded clinically using the Decayed, Missing and Filled Teeth Index (DMFT). Results were analyzed statistically using the Student’s t-test or analysis of variance. Results: Caries prevalence was 58% and 62% in SG and CG, respectively. DMFT index was 28.3 ± 6.6 in SG and 21.4 ± 6.07 in CG (p < 0.01). Mean number of decayed teeth was higher in SG (3.1) compared to CG (1.8) (p=0.047). Mean number of missing teeth were 25.2 and 16.4 in SG and CG respectively (p<0.05). DMFT scores were higher in SG in all the age groups (p < 0.01). Mean number of teeth per person needing treatment was 3.4 in SG and 1.9 in CG (p= 0.037). The need for restorative dental care was significantly lower in the SG (0.8 teeth per person) than in the CG (1.7 teeth per person) (p = 0.043). Conclusions: Institutionalized psychiatric patients have significantly worse dental status and more dental treatment needs than non-psychiatric patients.
A Diet Rich in Saturated Fat and Cholesterol Aggravates the Effect of Bacterial Lipopolysaccharide on Alveolar Bone Loss in a Rabbit Model of Periodontal Disease
(MDPI, 2020) Varela-López, Alfonso; Bullon, Pedro; Ramírez-Tortosa, César L.; Navarro-Hortal, María D.; Robles-Almazán, María; Bullón de la Fuente, Beatriz; Quiles, José L.; Universidad de Sevilla. Departamento de Estomatología
Increasing evidence connects periodontitis with a variety of systemic diseases, including metabolic syndrome, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). The proposal of this study was to evaluate the role of diets rich in saturated fat and cholesterol in some aspects of periodontal diseases in a lipopolysaccharide (LPS)-induced model of periodontal disease in rabbits and to assess the influence of a periodontal intervention on hyperlipidemia, atherosclerosis, and NAFLD progression to non-alcoholic steatohepatitis. Male rabbits were maintained on a commercial standard diet or a diet rich in saturated fat (3% lard w/w) and cholesterol (1.3% w/w) (HFD) for 40 days. Half of the rabbits on each diet were treated 2 days per week with intragingival injections of LPS from Porphyromonas gingivalis. Morphometric analyses revealed that LPS induced higher alveolar bone loss (ABL) around the first premolar in animals receiving standard diets, which was exacerbated by the HFD diet. A higher score of acinar inflammation in the liver and higher blood levels of triglycerides and phospholipids were found in HFD-fed rabbits receiving LPS. These results suggest that certain dietary habits can exacerbate some aspects of periodontitis and that bad periodontal health can contribute to dyslipidemia and promote NAFLD progression, but only under certain conditions.
A Microstructure Insight of MTA Repair HP of Rapid Setting Capacity and Bioactive Response
(MDPI, 2020) Jiménez Sánchez, María del Carmen; Segura Egea, Juan José; Diaz Cuenca, Aránzazu; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla
Mineral trioxide aggregate (MTA) is considered a bioactive endodontic material, which promotes natural mineralization at the material-tooth tissue interface. MTA Repair HP stands out because of the short setting time and the quick and effective bioactive response in vitro. The bioactivity, depens on material composition and microstructure. This work is devoted to analyze MTA Repair HP microstructural features, of both the powder precursor and set material, to get insights into the material physicochemical parameters—functionality performance relationships. Transmission electron microscopy (TEM), and field emission gun scanning electron microscopy (FEG-SEM) coupled with energy-dispersive X-ray (EDX) analyses were performed. X-ray diffraction (XRD) measurements were carried out at different times to investigate setting process. Bioactivity evaluation in vitro was carried out by soaking the processed cement disk in simulated body fluid (SBF). The presented results point out those MTA Repair HP precursor material characteristics of tricalcium silicate particles of nanometric size and high aspect ratio, which provide an elevated surface area and maximized components dispersion of calcium silicate and very reactive calcium aluminate. The MTA Repair HP precursor powder nanostructure and formulation, allows a hydration process comprising silicate hydrate structures, which are very effective to achieve both fast setting and efficient bioactive response.
A morphometric study of the secretory granules of the granular duct in the submaxillary gland of the rat following stimulation with noradrenalin and isoproterenol
(F HERNANDEZ, 1990) Gutierrez, M. S.; Galera, H.; Bullon, Pedro; Hevia, A.; Dorado-Ocaña, Manuel E.; Universidad de Sevilla. Departamento de Anatomía y Embriología Humana; Universidad de Sevilla. Departamento de Estomatología
In the present work, we carry out a morphometric analysis, at ultrastructural level, of the secretory granules of the granular undulated duct of the submaxillary gland of the rat, under basal conditions (Control Group or I), following stimulation for 10 minutes with 2 mg1100 g weight of Isoproterenol (Group 11), and following stimulation with 2 gamrnas/100 g weight of Noradrenalin for the same time as in the former case. It is seen that in general, Noradrenalin produces the appearance of a greater number of small granules than does Isoproterenol or the control group; and that Isoproterenol induces the presence of larger-sized granules than does Noradrenalin.
A morphometric study of the secretory granules of the granular duct in the submaxillary gland of the rat following stimulation with noradrenalin and isoproterenol
(Universidad de Murcia.Departamento de Biología Celular e Histología. F. Hernández, 1990-08-29) Gutierrez Marín, María Soledad; Galera Ruiz, Hugo; Bullon, Pedro; Hevia Alonso, Antonio; Dorado-Ocaña, Manuel E.; Universidad de Sevilla. Departamento de Anatomía y Embriología Humana; Universidad de Sevilla. Departamento de Cirugía; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla. Departamento de Farmacología, Pediatría y Radiología; Universidad de Sevilla. Departamento de Anatomía y Embriología Humana; Universidad de Sevilla. Departamento de Estomatología
In the present work, we carry out a morphometric analysis, at ultrastructural level, of the secretory granules of the granular undulated duct of the submaxillary gland of the rat, under basal conditions (Control Group or I), following stimulation for 10 minutes with 2 mg1100 g weight of Isoproterenol (Group 11), and following stimulation with 2 gamrnas/100 g weight of Noradrenalin for the same time as in the former case. It is seen that in general, Noradrenalin produces the appearance of a greater number of small granules than does Isoproterenol or the control group; and that Isoproterenol induces the presence of larger-sized granules than does Noradrenalin.
A non-interventional Study documenting use and success of tissue level implants
(2020-07-04) Díaz-Castro, Carmen M; Lázaro-Calvo, Pedro; Gil, Francisco Javier; Fernández Palacín, Ana; Ríos-Santos, J.V.; Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública; Universidad de Sevilla. Departamento de Estomatología
Numerous randomised controlled multicentric studies have investigated various responses to different treatment modalities with dental implants. These studies do not always show the results of daily practice as they are performed under controlled and strict clinical conditions. This multicentric, non-interventionist trial aimed to document the behaviour of implants when used in daily dental practice, without inclusion or exclusion criteria. One hundred and ninety-six screw-shaped, tissue-level implants were placed, and each clinician decided which implant, surgical loading and prosthetic protocol to use. At surgery, data related to the implants were recorded. Additionally, the crestal bone level changes were evaluated for up to two years of follow-up. Two implants were lost before they were loaded. The success rate was 98.31%, and the survival rate was 98.79%. The implant stability quotient (ISQ) at surgery was 68.61 ± 10.35 and at 2 years was 74.39 ± 9.64. The crestal–shoulder distances were 1.25 ± 1.09 mm and 1.68 ± 1.07 mm in the mesial and distal aspects on the day of surgery, respectively, and 2.04 ± 0.91 and 2.16 ± 0.99 mm at 2 years, respectively. At 2 years, 69.3% of the patients were highly satisfied. The use of implants under standard conditions seemed to have success rates similar to their placement in controlled studies.
A Prospective, Double-Blind, Randomized, Controlled Clinical Trial in the Gingivitis Prevention with an Oligomeric Proanthocyanidin Nutritional Supplement
(Hindawi, 2017) Díaz Sánchez, Rosa María; Castillo Dalí, Gabriel; Fernández-Olavarría, Ana; Mosquera Pérez, Regina María; Delgado Muñoz, José María; Gutiérrez Pérez, José Luis; Torres-Lagares, Daniel; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla. CTS523: Innovación y Desarrollo en Técnicas y Fundamentos de Cirugía Bucal y Craneofacial
Aim. To evaluate the effectiveness on tissue response of the new nutritional supplement made of oligomeric proanthocyanidins in induced gingivitis after 21 days of use. Material and Methods. A prospective, double-blind, randomized, controlled clinical trial was carried out on 20 patients; it is divided into an experimental group and a control group after fulfilling the selection criteria. Patients had to come 4 times during the study to register the Silness and Löe index, the gingival bleeding index, the plaque index, the inflammatory crevicular fluid study (IL6), and the changes in the brightness of the gingiva. No complementary hygiene methods were allowed during the 21 days. Results. The Silness and Löe index was higher in the control group than in the experimental group, reaching a twofold difference between the groups (p < 0 0001). The gingival bleeding index also supports this fact, since the bleeding was lower in the experimental group (p < 0 005). However, the dental plaque on the tooth surface according to the plaque index was 33% higher in the experimental group (p < 0 006). Some differences in the IL-6 were found in the crevicular fluid (p < 0 0001). Conclusion. Oligomeric proanthocyanidins have an effect on the periodontal tissue’s health. No effects on the accumulation of plaque on the tooth surface were found, so further studies are needed to determine the nature of the plaque.
A Radiographical and clinical comparison of immediate vs. early loading (4 weeks) implants with a new thermo-chemically treated-surface; a randomized clinical trial
(MDPI, 2021-01-29) Albertini, Matteo; Herrero Climent, Federico; Díaz-Castro, Carmen M; Nart, José; Fernández Palacín, Ana; Ríos-Santos, J.V.; Herrero Climent, Mariano; Universidad de Sevilla. Departamento de Estomatología
Background: Implant dentistry has evolved over time, resulting in better treatment outcomes for both patients and clinicians. The aim of this trial was to test whether the immediate loading of implants with a platform-switching design influences the marginal bone level, compared to four-week loading, after one year of follow-up. Moreover, a comparison of clinical data regarding implant survival, implant stability, and patient-reported outcome measures (PROMs) was conducted. Methods: Klockner® VEGA® implants with a ContacTi® surface were placed in partially edentulous patients in the posterior areas. Group A received an immediately loaded prosthesis (one week) and Group B received an early-loaded prosthesis (four weeks). All abutments were placed at the time of surgery. Radiographic and clinical data were recorded. Results: Twenty-one patients were treated (35 implants). No implants were lost during the study. The final marginal bone level did not show differences between groups. The bone loss at 12 months at the implant level was 0.00 mm for both groups (median). The final implant quotient stability (ISQ) values did not differ between groups (median 73 and 70.25), nor did the other clinical parameters or PROMs. Conclusions: The results suggest that neither of the loading protocols with the implants used influenced the marginal bone level—not the osseointegration rate, clinical conditions, or PROMs.
A review of the influence of periodontal treatment insystemic diseases
(Wiley, 2019-02) Falcao, Artur; Bullon, Pedro; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla. CTS-113: Investigación Etiología y Patogenia Periodontal, Patología Oral y Enfermedades Musculares
The effects and consequences of periodontal diseases might not be confined to the oral cavity. A great body of evidence has arisen supporting the claim demonstrating an association with several systemic conditions and diseases. With different levels of evidence, an association between periodontal disease and cardiovascular disease, diabetes, psoriasis, rheumatoid arthritis, pregnancy outcomes and respiratory diseases has been established. However, the true nature of this association, if it is causal, still remains elusive. For a better understanding of the complex relationships linking different conditions, interventional studies now begin to focus on the possible outcomes of periodontal treatment in relation to the events, symptoms and biomarkers of several systemic disorders, assessing if periodontal treatment has any impact on them, hopefully reducing their severity or prevalence. Therefore, we proceeded to review the recent literature on the subject, attempting to present a brief explanation of the systemic condition or disease, what proposed mechanisms might give biological plausibility to its association with periodontal disease, and finally and more importantly, what data are currently available pertaining to the effects periodontal treatment may have. Raising awareness and discussing the possible benefits of periodontal treatment on overall systemic health is important, in order to change the perception that periodontal diseases are only limited to the oral cavity, and ultimately providing better and comprehensive care to patients.
A review on CAD/CAM Yttria-stabilized Tetragonal Zirconia Polycrystal (Y-TZP) and Polymethyl Methacrylate (PMMA) and their biological behavior
(MDPI, 2022) Herráez Galindo, Cristina; Rizo-Gorrita, María; Maza Solano, Serafín; Serrera Figallo, María de los Ángeles; Torres-Lagares, Daniel; Universidad de Sevilla. Departamento de Estomatología
Yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) and polymethyl methacrylate (PMMA) are used very often in dentistry. Y-TZP is the most widely used zirconia dental ceramic, and PMMA has classically been used in removable prosthesis manufacturing. Both types of materials are commercialized in CAD/CAM system blocks and represent alternatives for long-lasting temporary (PMMA) or definitive (Y-TZP) implantological abutments. The aim of the present work is to reveal that human gingival fibroblasts (HGFs) have a favorable response when they are in contact with Y-TZP or PMMA as a dental implant abutment or implant-supported fixed prosthesis, and also to review their principal characteristics. We conducted an electronic search in the PubMed database. From an initial search of more than 32,000 articles, the application of filters reduced this number to 5104. After reading the abstracts and titles, we reduced the eligible articles to 23. Ultimately, we have included eight articles in this review.
A Systematic Review and Meta-Analysis of Systemic and Local Antibiotic Therapy in the Surgical Treatment of Peri-Implantitis
(MDPI, 2023-07-24) Baus Domínguez, María; Bakkali, S.; Hermida-Cabrera, P.; Serrera Figallo, María de los Ángeles; Gutiérrez Pérez, José Luis; Torres-Lagares, Daniel; Universidad de Sevilla. Departamento de Estomatología
Given the existing controversy regarding the use of antibiotics in the treatment of peri-implantitis, this systematic review and meta-analysis aim to ascertain how beneficial the role of systemic and local antibiotics is in peri-implant surgical therapy, considering the harmful effects that they represent and the abuse of antibiotics in terms of global health. (2) Methods: To determine the therapeutic efficacy of the administration of antibiotics in the surgical treatment of peri-implantitis in terms of probing pocket depth (PPD) and bleeding on probing (BoP), electronic and manual bibliographic searches were carried out in the Embase and PubMed databases, collecting data that related to before and after treatment. (3) Results: The adjunctive use of local antibiotics provides significant improvements in PPD (MD = 1.29; 95% CI: 0.56 to 2.02; p ≤ 0.0006; I2 = 0%) when compared with surgical treatment alone. No significant differences were found in the other subgroup; that is, the use of systemic antibiotics did not significantly improve PPD changes in the surgical treatment of peri-implantitis (MD = 0.40; 95% CI: −0.15 to 0.95; p = 0.15; I2 = 0). (4) Conclusions: The use of local antibiotics in the surgical treatment of peri-implantitis seems to offer treatment improvements in terms of PPD and BoP, unlike that observed with the use of systemic antibiotics. However, these results should be taken with caution as they also depend on the type of surgical technique used, whether regenerative or resective. More research is needed on this topic to understand the role of local and systemic antibiotics in the treatment of peri-implantitis.
A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease
(2016-09-07) Valera-López, Alfonso; Giampieri, Francesca; Bullon, Pedro; Battino, Maurizio; Quiles, José L.; Universidad de Sevilla. Departamento de Estomatología
Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages health-promoting bacteria and maintenance of oral-hygiene. The role of nutrition in different chronic inflammatory diseases has been the subject of an increasing body of research in the last decades. In this sense, there has been an important increase in the volume of research on role of nutrition in periodontitis since the diet has known effects on the immune system and inflammatory cascades. Minerals play a key role in all these processes due to the multiple pathways where they participate. To clarify the role of the different minerals in the establishment, progression and/or treatment of this pathology, a systemically review of published literature cited in PubMed until May 2016 was conducted, which included research on the relationship of these elements with the onset and progression of periodontal disease. Among all the minerals, calcium dietary intake seems important to maintain alveolar bone. Likewise, dietary proportions of minerals that may influence its metabolism also can be relevant. Lastly, some observations suggest that all those minerals with roles in immune and/or antioxidant systems should be considered in future research.
Ability of salivary biomarkers in the prognostic of systemic and buccal inflammation
(2017) Gutiérrez Corrales, Aída; Campano-Cuevas, Elena; Castillo-Dalí, Gabriel; Torres-Lagares, Daniel; Gutiérrez Pérez, José Luis; Universidad de Sevilla. Departamento de Estomatología
Nowadays, there is a growing interest in using saliva as an alternative sample for the diagnosis, prediction and progression of several diseases. It has been established that some molecules found in saliva are related to oral inflammatory processes and systemic health status. Furthermore, it is known that saliva is crucial for the carrying out of different functions in the oral cavity and its role in the local modulation of inflammatory and immune response is being thoroughly studied by the health research community. The aim of this review is to analyze the most important biomarkers which have been utilized in biomedicine during the last two decades in order to establish a correlation between certain specific salivary biomarkers and systemic inflammation. Then, we discuss the utility of total proteins, immunoglobulin A and alpha-amylase as biomarkers for the prognostic of local inflammation after oral surgery.
Accuracy of implant casts generated with conventional and digital Impressions: an in vitro study
(MDPI AC, 2018-07-27) Ribeiro, Paulo; Herrero Climent, Mariano; Díaz-Castro, Carmen M; Ríos-Santos, J.V.; Padrós, Roberto; Gil Mur, Javier; Falcao, C.; Universidad de Sevilla. Departamento de Estomatología
Purpose: The aim of this study was to compare the accuracy of digital dental impressions with the accuracy of impressions obtained via conventional techniques. Methods: Two different master models were created, one with parallel implants (model 1) and the other with non-parallel implants (model 2). These reference master models included 4 Klockner KL RP implants (Klockner Implant System SA, Barcelona, Spain), which were juxta-placed and equidistant in the intermentoneal region. In model 1 the implants were placed parallel to each other, whereas in model 2 the implants were placed such that there was a divergence angle of 15° between the more distal implants, and a convergence angle of 15° between the two central implants. A total of four types of impressions were obtained from model 1 (four groups, n = 10 each), including closed tray impressions with replacement abutments; open tray impression groups for dragging copings, without splinting; open tray impressions for ferrules; and impressions obtained using the 3MTM True Definition Scanner system. For model 2 three groups were created (three groups, n = 10 each), including closed tray impressions with replacement abutments; open tray impression for dragging copings, without splinting; and impressions obtained using the 3MTM True Definition Scanner system. The master models and the models obtained using conventional methods were digitalized in order to compare them via an extraoral high-resolution scanner (Imetric IScan D104i, Porretruy, Switzerland). The STL (Stereo Lithography (format for transferring 3 dimensional shape information)) digital values were loaded into reverse-engineering software and superimposed with their respective STL master models in order to evaluate deviations in three dimensions. We then analyzed the squares of the deviations in the three axes and evaluated the median and the sum of the deviation square. Statistical analysis was performed using the IBM Corp. Released 2016. IBM SPSS Statistics for Windows, Version 24.0. Armonk, NY: IBM Corp. The normality of the distributions was analyzed according to a Kolmogorov-Smirnov test. The median comparison was performed using the differences between the medians, analyzed using non-parametric Kruskal-Wallis and Mann-Whitney tests with a significance level of p < 0.05. Results: For model 1, the deviations of the digital impressions were smaller than those associated with the conventional techniques. The sum value in group D was 1,068,292, which was significantly lower than those of groups A, B, and C, which were shown to be 2,114,342, 2,165,491, and 1,265,918, respectively. This improvement was not observed when using model 2, however, where the conventional techniques yielded similar results. Group F simultaneously presented the lowest total square sum of the three deviations (1,257,835), indicating a significantly higher accuracy for this group in model 2, while the sum values were 1,660,975 and 1,489,328 for groups E and G, respectively. Conclusion: Digital impressions of full-arch models were able to achieve the accuracy of conventional impressions in an in vitro model. Nevertheless, further in vivo studies are needed to validate these in vitro results.
Actin cytoskeletal organization in human osteoblasts grown on different dental titanium implant surfaces
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2007-10-01) Salido Peracaula, Mercedes; Vilches Pérez, José Ignacio; Gutiérrez Pérez, José Luis; Vilches Troya, José; Universidad de Sevilla. Departamento de Estomatología
The understanding of the cellular basis of osteoblastic cell-biomaterial interaction is crucial to the analysis of the mechanism of osseointegration. Cell adhesion is a complex process that is dependent on the cell types and on the surface microtopography and chemistry of the substrate. We have studied the role of microtopography in modulating cell adhesion, in vitro, using a human osteoblastic cell line for the assessment of actin cytoskeletal organization. Through application of CLSM combining reflection and fluorescence, 2D or 3D images of cytoskeleton were obtained. On smooth surfaces, Ti CP machined, predominantly planar bone cells with an axial ratio of 1.1 were randomly oriented, with stress fibers running in all directions, and thin filopodia. On T iCP Osseotite ® surfaces the osteoblastic cells conformed to the irregular terrain of the sustrate with focal adhesion sites only established on the relative topographical peaks separated for a longer distance than in the machined surface, and defined wide lamellopodia and long filopodia, with enhanced expression of stress fibers, forming large clear focal contacts with the rough surface. The cytoskeletal organization of cells cultured on rough titanium supports an active role for the biomaterial surface in the events that govern osteoblastic cell adhesion. The results enforce the role of the rough sustrate surface in affecting osteoblastic cell adhesion and provide valuable information for the design of material surfaces that are required for the development of an appropriate osteogenic surface for osteoblastic anchorage, compared to machined surface, in dental implants.
Active unilateral condylar hyperplasia: Assessment of the usefulness of single photon emission computed tomography
(Medicina Oral S.L., 2020) Guerrero Arenillas, Vanesa; González Padilla, Juan David; Díaz Sánchez, Rosa María; Torres-Lagares, Daniel; Gutiérrez Pérez, José Luis; Gutiérrez Corrales, Aída; Serrera Figallo, María de los Ángeles; Universidad de Sevilla. Departamento de Estomatología; Universidad de Sevilla. CTS523: Innovación y Desarrollo en Técnicas y Fundamentos de Cirugía Bucal y Craneofacial
Background: This study aims to evaluate whether the uptake difference by the condyles evaluated using single photon emission computed tomography (SPECT) examination is useful for predicting the activity of the feature and the advance of this pathology. Material and Methods: An observational and prospective study has been carried out on nine patients affected by unilateral condylar hyperplasia (UCH) with complete bone maturation, with a follow-up over 18 months. At the beginning of the study, a test-battery was conducted including dental casts, articular examination, teleradiography and cephalometry, computed tomography and SPECT, creating two groups of patients from a difference in uptake between both condyles greater than 10% over the follow-up period. Evolution of data obtained with the rest of the diagnostic tests were compared to confirm UCH activity predicted by SPECT. Results: The comparison of both groups did not show hardly any significant differences, with little clinical signifi cance. Deviation of the mandibular line, the size of the branches or condyles behaved similarly in both study groups. Conclusions: From the data obtained in our study, we can conclude that the use of the difference in uptake be tween both condyles by applying the SPECT technique is not a valid approach for predicting clinical activity in cases of UCH.
Actualización de las técnicas de odontosección en los dientes con afectación de la furcación
(Ediciones avances, S.L., 1994) Machuca-Portillo, Guillermo; Machuca Portillo, María del Carmen; Martínez-Sahuquillo Márquez, Ángel; Velasco-Ortega, Eugenio; Ríos-Santos, J.V.; Bullon, Pedro; Universidad de Sevilla. Departamento de Estomatología
Una de las complicaciones más importantes que pueden surgir cuando se trata una periodontitis es que alguno de los dientes multirradiculares tenga afectada la furca. De cualquier forma, el pronóstico de dicho diente va a depender de un diagnóstico adecuado, que no siempre es posible al princpio por su dificultad, y de otros factores como la anatomía del diente o la destreza del paciente para mantener la higiene en la zona. En los últimos tiempos han surgido técnicas sofisticadas para el tratamiento de estos dientes (regeneración tisular guiada) que, si bien tienen utilidad en determinados casos, no deben hacernos olvidar otras técnicas no por más antiguas menos indicadas en ciertas circunstancias. Entre ellas, las técnicas de odontosección nos ofrecen la posibilidad de mantener molares o racíces estratégicas en la boca, que pueden evitarnos la realización de reconstrucciones más arriesgadas y costosas, incluso valorando las variadas controversias que surgen entre los diferentes autores cuando estudian dicho proceso terapéutico.
Actualización en microimplantes de relleno perioral atendiendo a su permanencia
(Inspira Network Group S.L., 2012-10-09) Aced Jiménez, Elena; Ruiz de León Hernández,Gonzalo; Hernández Pacheco, Esther; Torres-Lagares, Daniel; Gutiérrez Pérez, José Luis; Universidad de Sevilla. Departamento de Estomatología
Introducción y objetivo El uso de materiales de relleno facial para la corrección de arrugas, pliegues y otros defectos es cada vez más demandado por nuestros pacientes. Se trata de materiales que al ser infiltrados provocan un aumento de volumen. Pueden clasificarse en función del tiempo de permanencia en el cuerpo en temporales o biodegradables (entre 4 y 8 meses), semipermanentes (entre 12 y 18 meses) y permanentes (no biodegradables). Nuestro trabajo tiene por objeto repasar los materiales de relleno que actualmente están aprobados por la Agencia del Medicamento en septiembre de 2010. Material y métodos Hemos revisado a través de la página web oficial de la Agencia Española del Medicamento los materiales de rellenos aprobados por la misma en septiembre de 2010, para posteriormente hacer una revisión de la literatura científica más reciente sobre ellos. Resultados Estos son: el ácido hialurónico, colágeno y agarosa para los materiales temporales; el ácido poliláctico, la hidroxiapatita de calcio y la policaprolactona como materiales semipermanentes; y el polimetilmetracrilato y las acrilamidas en el grupo de los materiales permanentes. Discusión Las características ideales que debería cumplir un relleno facial son ser biocompatible, no cancerígeno, no teratógeno, no migratorio y tener resultados satisfactorios con durabilidad. Estos tipos de materiales son productos sanitarios y deben cumplir la normativa de la Agencia Española del Medicamento. Por tanto, solo deben ser utilizados por profesionales cualificados y preparados específicamente en este terreno. Conclusiones Los rellenos temporales son los que más se emplean con fines estéticos. Sin embargo, es necesario el conocimiento de la naturaleza de cada material, sus indicaciones y las posibles complicaciones que pueden aparecer tras su uso para poder así sacar el máximo beneficio y obtener los mejores resultados posibles.

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