NameMéndez Ardoy, Alejandro
DepartmentQuímica Orgánica
Knowledge areaQuímica Orgánica
Professional categoryInvestigador Contratado (Ramón y Cajal)
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  • No. publications

    7

  • No. visits

    293

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    291


 

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Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection selectivity

Ortega Caballero, Fernando; Santana Armas, Maria L.; Tros de Ilarduya, Conchita; Di Giorgio, Christophe; Tripier, Raphael; Le Bris, Nathalie; Ollier, Cedric; Ortiz Mellet, Carmen; García Fernández, José Manuel; Jiménez Blanco, José Luis; Méndez Ardoy, Alejandro (Royal Society of Chemistry, 2024)
A novel family of precision-engineered gene vectors with well-defined structures built on trehalose and trehalose-based ...
Article
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A 3D Peptide/[60]Fullerene Hybrid for Multivalent Recognition

Gallego, Iván; Ramos-Soriano, Javier; Méndez Ardoy, Alejandro; Cabrera González, Justo; Lostalé Seijo, Irene; Illescas, Beatriz M.; Reina, José J.; Martín, Nazario; Montenegro, Javier (Wiley-Blackwell, 2022)
Fully substituted peptide/[60]fullerene hexakis-adducts offer an excellent opportunity for multivalent protein recognition. ...
Article
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Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery

Méndez Ardoy, Alejandro; Díaz Moscoso, Alejandro; Ortiz Mellet, Carmen; Di Giorgio, Christophe; Vierling, Pierre; Benito, Juan M.; García Fernández, José Manuel (Royal Society of Chemistry, 2015)
Polycationic amphiphilic cyclodextrins (paCDs) have been shown to behave as efficient non-viral gene carriers paralleling ...
Article
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Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo

Aranda, Cristina; Urbiola, Koldo; Méndez Ardoy, Alejandro; García Fernández, José Manuel; Ortiz Mellet, Carmen; Ilarduya, C.T. (Elsevier, 2013)
Aim Development and evaluation of a new targeted gene delivery system by first preforming self-assembled nanocomplexes ...
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Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery

Díaz Moscoso, Alejandro; Guilloteau, Nicolas; Bienvenu, Céline; Méndez Ardoy, Alejandro; Jiménez Blanco, José Luis; Benito Hernández, Juan Manuel; Le Gourriérec, Loïc; Di Giorgio, Christophe; Vierling, Pierre; Defaye, Jacques; Ortiz Mellet, Carmen; García Fernández, José Manuel (Elsevier, 2011)
Fully homogeneous facial amphiphiles consisting in a cyclodextrin (CD) platform onto which a polycationic cluster and a ...
Patent. Invention
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Ciclooligosacáridos anfifílicos policatiónicos y su uso como transportadores moleculares

Ortiz Mellet, Carmen; Méndez Ardoy, Alejandro; Gómez García, Marta; Sevillano Trapero, Natalia; Girón González, María Dolores; Salto González, Rafael; Santoyo González, Francisco; García Fernández, José Manuel (Oficina Española de Patentes y Marcas (OEPM), 2011)
Ciclooligosacáridos anfifílicos policatiónicos y su uso como transportadores moleculares. La presente invención se refiere ...
Article
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Self-association of a naphthalene-capped-β-cyclodextrin through cooperative strong hydrophobic interactions

González-Álvarez, M.José; Méndez Ardoy, Alejandro; Benito Hernández, Juan Manuel; García Fernández, José Manuel; Mendicuti, Francisco (Elsevier, 2011)
NMR, circular dichroism and fluorescence techniques were used to study the structure in solution of a new β-cyclodextrin ...