Data

NameAngulo Álvarez, Jesús
DepartmentQuímica Orgánica
Knowledge areaQuímica Orgánica
Professional categoryBeatriz Galindo (Investigador distinguid
E-mailRequest
         

  Statistics

  • Items

    19

  • Visits

    777

  • Downloads

    914

  Publications

 

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Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter

Furze, Christopher M.; Delso, Ignacio; Casal, Enriqueta; Seddon, Chloe; Brown, Chelsea M.; Parker, Hadyn L.; Radhakrishnan, Anjana; Pacheco Gómez, Raul; Stansfeld, Phillip J.; Angulo Álvarez, Jesús; Cameron, Alexander D.; Fullam, Elizabeth (American Society for Biochemistry and Molecular Biology Inc., 2021-01-01)
The Mycobacterium tuberculosis (Mtb) LpqY-SugABC ATPbinding cassette transporter is a recycling system that imports trehalose ...
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Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity

Latorre Muro, Pedro; Baeza, Josue; Hurtado Guerrero, Ramón; Hicks, Thomas; Delso, Ignacio; Hernández Ruiz, Cristina; Velázquez Campoy, Adrián; Lawton, Alexis J.; Angulo Álvarez, Jesús; Denu, John M.; Carrodeguas, José Alberto (American Society for Biochemistry and Molecular Biology Inc., 2021-01-01)
Acetylation is known to regulate the activity of cytosolic phosphoenolpyruvate carboxykinase (PCK1), a key enzyme in ...
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Fucosidases from the human gut symbiont Ruminococcus gnavus

Wu, Haiyang; Rebello, Osmond; Owen, C. David; Walpole, Samuel; Bennati Granier, Chloe; Ndeh, Didier; Monaco, Serena; Angulo Álvarez, Jesús (Springer, 2021-01-01)
The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation ...
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Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide

Nepravishta, Ridvan; Monaco, Serena; Distefano, Marco; Rizzo, Roberto; Cescutti, Paola; Angulo Álvarez, Jesús (Frontiers Media S.A., 2021-01-01)
Biofilms confine bacterial cells within self-produced matrices, offering advantages such as protection from antibiotics ...
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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7

Bidula, S.M.; Cromer, B.A.; Walpole, S.; Angulo Álvarez, Jesús; Stokes, Leanne (Nature Research (part of Springer Nature): Fully open access journals, 2019-01-01)
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens ...
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Spatially Resolved STD-NMR Applied to the Study of Solute Transport in Biphasic Systems: Application to Protein-Ligand Interactions

Nepravishta, Ridvan; Monaco, Serena; Muñoz García, Juan Carlos; Khimyak, Yaroslav Z.; Angulo Álvarez, Jesús (SAGE Publications, 2019-01-01)
Fluid biphasic systems are one of the most interesting dynamic systems in chemistry and biochemistry. In nuclear magnetic ...
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Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design

Beekman, Andrew M.; Cominetti, Marco M. D.; Walpole, S.; Prabhu, Saurabh; O'Connell, Maria A.; Angulo Álvarez, Jesús; Searcey, Mark (Royal Society of Chemistry: Open Access, 2019-01-01)
The development of protein–protein interaction (PPI) inhibitors with therapeutic value is of increasing importance as the ...
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Ginsenosides act as positive modulators of P2X4 receptors

Dhuna, K.; Felgate, M.; Bidula, S.M.; Walpole, S.; Bibic, L.; Cromer, B.A.; Angulo Álvarez, Jesús; Sanderson, J.; Stebbing, M.J.; Stokes, L. (American Society for Pharmacology and Experimental Therapeutics (ASPET), 2019-01-01)
We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators ...
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Correction: Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design

Beekman, Andrew M.; Cominetti, Marco M. D.; Walpole, S.; Prabhu, Saurabh; O'Connell, Maria A.; Angulo Álvarez, Jesús; Searcey, Mark (Royal Society of Chemistry: Open Access, 2019-01-01)
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Spin Saturation Transfer Difference NMR (SSTD NMR): A New Tool to Obtain Kinetic Parameters of Chemical Exchange Processes

Quirós, María Teresa; Macdonald, Colin; Angulo Álvarez, Jesús; Muñoz, María Paz (Journal of Visualized Experiments (JoVE), 2016-01-01)
This detailed protocol describes the new Spin Saturation Transfer Difference Nuclear Magnetic Resonance protocol (SSTD ...
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The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain

Aroca Aguilar, Ángeles; Cruz Gallardo, Isabel; Díaz Moreno, Irene; Angulo Álvarez, Jesús; Gunzburg, Menachen J.; Sivakumaran, Andrew; Yoon, Je-Hyun (Taylor & Francis, 2014-01-01)
T-cell intracellular antigen-1 (TIA-1) is a key DNA/RNA binding protein that regulates translation by sequestering target ...
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Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1

Muñoz García, Juan Carlos; García Jiménez, M. José; Carrero, Paula; Canales, Ángeles; Jiménez Barbero, Jesús; Martín Lomas, Manuel; Imberty, Anne; Paz, José L. de; Angulo Álvarez, Jesús; Lortat Jacob, Hughes; Nieto, Pedro M. (Oxford University Press, 2014-01-01)
Heparin-like saccharides play an essential role in binding to the fibroblast growth factor (FGF)-1 and to their membrane ...
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A STD-NMR Study of the Interaction of the Anabaena Ferredoxin-NADP+ Reductase with the Coenzyme

Antonini, Lara V.; Peregrina, José R.; Angulo Álvarez, Jesús; Medina, Milagros; Nieto, Pedro M. (MDPI, 2014-01-01)
Ferredoxin-NADP+ reductase (FNR) catalyzes the electron transfer from ferredoxin to NADP+ via its flavin FAD cofactor. To ...
PhD Thesis
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Insights on the structure and dynamics of glycosaminoglycans and their interactions with langering: NMR and computational studies

Angulo Álvarez, Jesús; Nieto Mesa, Pedro Manuel; Muñoz García, Juan Carlos (2013-10-25)
La determinación de las estructuras tridimensionales de los oligosacáridos así como la comprensión de las bases moleculares ...
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Synthesis of chondroitin/dermatan sulfate-like oligosaccharides and evaluation of their protein affinity by fluorescence polarization

Maza Pérez, Susana; Kayser Gutiérrez, María del Mar; Macchione, Giuseppe; López Prados, Javier; Angulo Álvarez, Jesús; Paz Carrera, Jose Luis de (Royal Society of Chemistry (Great Britain), 2013-01-01)
Here, we present a novel approach for the chemical synthesis of chondroitin and dermatan sulfate oligosaccharides. A key ...
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NMR studies on carbohydrate interactions with DC-SIGN towards a quantitative STD analysis

Guzzi, Cinzia; Muñoz García, Juan Carlos; Enriquez Navas, Pedro Miguel; Rojo, Javier; Angulo Álvarez, Jesús; Nieto, Pedro M. (De Gruyter, 2013-01-01)
The recent introduction of saturation transfer difference (STD) NMR has increased the tools for the study of protein–carbohydrate ...
PhD Thesis
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Interacciones de oligomanósidos con el anticuerpo 2g12 (anti vih-1). Estudios por RMN y modelización molecular

Angulo Álvarez, Jesús; Penadés Ullate, Soledad; Enriquez Navas, Pedro Miguel (2011-03-23)
En esta tesis doctoral, se ha abordado el estudio de las interacciones en disolución entre una serie de oligomanósidos, ...
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Fragment-based screening of the donor substrate specificity of human blood group B galactosyltransferase using saturation transfer difference NMR

Blume, Astrid; Angulo Álvarez, Jesús; Biet, Thorsten; Peters, Hannelore; Benie, Andrew J.; Palcic, Monica; Peters, Thomas (American Society for Biochemistry and Molecular Biology, 2006-01-01)
Saturation transfer difference NMR experiments on human blood group B α-(1,3)-galactosyltransferase (GTB) for the first ...
PhD Thesis
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Estudio de la estructura tridimensional y de la dinámica de oligosacáridos modelos de glicosaminoglicanos mediante RMN y simulaciones de dinámica molecular

Nieto Mesa, Pedro Manuel; Angulo Álvarez, Jesús (2002-01-01)
En esta Tesis Doctoral se presentan los estudios estructurales mediante espectroscopia de Resonancia Magnética Nuclear y ...