NameCánovas López, David
DepartmentGenética
Knowledge areaGenética
Professional categoryProfesor Titular de Universidad
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PhD Thesis
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Transcriptional regulation by the Velvet complex during development in Neurospora crassa

Cea Sánchez, Sara; Corrochano Peláez, Luis María; Cánovas López, David (2023)
Developmental transitions in fungi are key to their success in colonizing new habitats and adapting to stressful environmental ...
Article
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The Fungal Protein Mes1 Is Required for Morphogenesis and Virulence in the Dimorphic Phytopathogen Ustilago maydis

Cánovas López, David (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Polarized growth is a defining property of filamentous fungi, which plays an important role in different aspects of their ...
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Identification of an acetyl esterase in the supernatant of the environmental strain Bacillus sp. HR21-6

Sánchez Barrionuevo, Leyre; Mateos, Jesús; Fernández Puente, Patricia; Begines Aguilar, Paloma; Fernández-Bolaños Guzmán, José María; Gutiérrez Pozo, Gabriel; Cánovas López, David; Mellado Durán, María Encarnación (Elsevier, 2022)
Bacillus sp. HR21-6 is capable of the chemo- and regioselective synthesis of lipophilic partially acetylated phenolic ...
Article
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Light regulates the degradation of the regulatory protein VE-1 in the fungus Neurospora crassa

Gil Sánchez, María del Mar; Cea Sánchez, Sara; Luque, Eva M.; Cánovas López, David; Corrochano Peláez, Luis María (Springer Nature, 2022)
Background: Fungi use light as an environmental signal to regulate developmental transitions that are key aspects of their ...
Article
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Transcriptional regulation by the velvet protein VE-1 during asexual development in the fungus neurospora crassa.

Cea Sánchez, Sara; Corrochano Luque, María; Gutiérrez Pozo, Gabriel; Glass, N. Louise; Cánovas López, David; Corrochano Peláez, Luis María (American Society for Microbiology, 2022)
Asexual reproduction in fungi facilitates the dispersal and colonization of new substrates and, in pathogenic fungi, allows ...
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An arsRB resistance operon confers tolerance to arsenite in the environmental isolate Terribacillus sp. AE2B 122

Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Torres Torres, José Miguel; Clemente, Rafael; Gutiérrez Pozo, Gabriel; Mellado Durán, María Encarnación; Cánovas López, David (Oxford University Press, 2021)
Terribacillus sp. AE2B 122 is an environmental strain isolated from olive-oil agroindustry wastes. This strain displays ...
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Evidence for an arginine-dependent route for the synthesis of NO in the model filamentous fungus Aspergillus nidulans

Franco Cano, Antonio; Marcos Rodríguez, Ana Teresa; Strauss, Joseph; Cánovas López, David (Wiley-Blackwell, 2021)
Nitric oxide (NO) is a signalling molecule in eukaryotic and prokaryotic organisms. NO levels transiently boost upon ...
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The Cell Wall Integrity Pathway Contributes to the Early Stages of Aspergillus Fumigatus Asexual Development

Rocha, Marina Campos; Fabri, João Henrique Tadini Marilhano; Simões, Isabelle Taira; Silva Rocha, Rafael; Hagiwara, Daisuke; da Cunha, Anderson Ferreira; Goldman, Gustavo Henrique; Cánovas López, David; Malavazi, Iran (American Society for Microbiology, 2020)
Aspergillus fumigatus is a major cause of human disease. The survival of this fungus is dependent on the cell wall ...
PhD Thesis
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Selección de una esterasa bacteriana con propiedades regioselectivas para la obtención de compuestos bioactivos

Sánchez Barrionuevo, Leyre; Cánovas López, David; Mellado Durán, María Encarnación (2019)
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Hybrid in silico/in vitro target fishing to assign function to “orphan” compounds of food origin – The case of the fungal metabolite atromentin

Dellafiora, Luca; Aichinger, Georg; Geib, Elena; Sánchez Barrionuevo, Leyre; Brock, Matthias; Cánovas López, David; Dall'Asta, Chiara; Marko, Doris (Elsevier, 2019)
Many small molecules of food origin may effect human health but lack an adequate description of their biological activity. ...
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Genome sequencing of evolved aspergilli populations reveals robust genomes, transversions in A. flavus, and sexual aberrancy in non-homologous end-joining mutants

Álvarez Escribano, Isidro; Sasse, Christoph; Bok, Jin Woo; Na, Hyunsoo; Amirebrahimi, Mojgan; Gutiérrez Pozo, Gabriel; Cea Sánchez, Sara; Marcos Rodríguez, Ana Teresa; Cánovas López, David (BMC, 2019)
BACKGROUND: Aspergillus spp. comprises a very diverse group of lower eukaryotes with a high relevance for industrial ...
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Evolution of asexual and sexual reproduction in the aspergilli

Ojeda López, M.; Chen, W.; Eagle, C.E.; Gutiérrez Pozo, Gabriel; Jia, W.L.; Swilaiman, S.S.; Huang, Z.; Park, H.S.; Yu, J.H.; Cánovas López, David; Dyer, P.S. (Westerdijk Fungal Biodiversity Institute, 2018)
Aspergillus nidulans has long-been used as a model organism to gain insights into the genetic basis of asexual and sexual ...
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High-throughput format for the phenotyping of fungi on solid substrates

Cánovas López, David; Studt, Lena; Marcos Rodríguez, Ana Teresa; Strauss, Joseph (Nature Publishing Group, 2017)
Filamentous fungi naturally grow on solid surfaces, yet most genetic and biochemical analyses are still performed in liquid ...
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Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

Vries, Ronald P. de; Aguilar Osorio, Guillermo; Riley, Robert; Wiebenga, Ad; Cánovas López, David (BioMed Central, 2017)
Background The fungal genus Aspergillus is of critical importance to humankind. Species include those with industrial ...
Patent. Invention
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Derivados acilados de carbohidratos, métodos de obtención y usos de los mismos

Mellado Durán, Encarnación; Fernández-Bolaños Guzmán, José María; Maya Castilla, Inés; Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Cánovas López, David; González Benjumea, Alejandro; López López, Óscar (Oficina Española de Patentes y Marcas (OEPM), 2016)
Derivados acilados de carbohidratos, métodos de obtención y usos de los mismos. La presente invención describe derivados ...
Patent. Invention
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Derivados acilados de polifenoles y/o carbohidratos, métodos de obtención y usos de los mismos

Mellado Durán, Encarnación; Fernández-Bolaños Guzmán, José María; Maya Castilla, Inés; Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Cánovas López, David; González Benjumea, Alejandro; López López, Óscar (Oficina Española de Patentes y Marcas (OEPM), 2016)
Derivados acilados de polifenoles y/o carbohidratos, métodos de obtención y usos de los mismos. La presente invención ...
PhD Thesis
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Actividades enzimáticas de terribacillus SP. AE2B 122 con aplicaciones medioambientales

Escobar Niño, Almudena; Mellado Durán, María Encarnación; Cánovas López, David (2016)
La búsqueda de nuevas fuentes de energías alternativas, sostenibles y renovables se ha convertido en un área de investigación ...
Patent. Invention
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Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación

Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Cánovas López, David; Mellado Durán, Encarnación; González Benjumea, Alejandro; López López, Óscar; Maya Castilla, Inés; Fernández-Bolaños Guzmán, José María (Oficina Española de Patentes y Marcas (OEPM), 2016)
Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación. La presente invención describe cepas microbianas ...
Patent. Invention
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Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación

Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Cánovas López, David; Mellado Durán, Encarnación; González Benjumea, Alejandro; López López, Óscar; Maya Castilla, Inés; Fernández-Bolaños Guzmán, José María (Oficina Española de Patentes y Marcas (OEPM), 2016)
Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación. La presente invención describe cepas microbianas ...
Patent. Invention
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Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación

Escobar Niño, Almudena; Sánchez Barrionuevo, Leyre; Cánovas López, David; Mellado Durán, Encarnación; González Benjumea, Alejandro; López López, Óscar; Maya Castilla, Inés; Fernández-Bolaños Guzmán, José María (Oficina Española de Patentes y Marcas (OEPM), 2016)
Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación. La presente invención describe cepas microbianas ...
Article
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Nitric oxide synthesis by nitrate reductase is regulated during development in Aspergillus

Marcos Rodríguez, Ana Teresa; Ramos Guelfo, María Salud; Marcos, José F.; Carmona, Lourdes; Strauss, Joseph; Cánovas López, David (Wiley-Blackwell, 2016)
Nitric oxide (NO) is a signalling molecule involved in many biological processes in bacteria, plants and mammals. However, ...
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A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria

Sánchez Barrionuevo, Leyre; González Benjumea, Alejandro; Escobar Niño, Almudena; García Gutiérrez, María Teresa; López López, Óscar; Maya Castilla, Inés; Fernández-Bolaños Guzmán, José María; Cánovas López, David; Mellado Durán, María Encarnación (Public Library of Science, 2016)
The chemical synthesis of new lipophilic polyphenols with improved properties presents technical difficulties. Here we ...
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Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication

Corrochano Peláez, Luis María; Kuo, Alan; Ávalos Cordero, Francisco Javier; Camino, Lola P.; Cánovas López, David; Cerdá Olmedo, Enrique; Gutiérrez Pozo, Gabriel; Luque Fobelo, Eva Milagros; Marcos Rodríguez, Ana Teresa; Ramírez Medina, Humberto; Miralles Durán, Alejandro; Olmedo López, María; Rodríguez Romero, Julio; García Tagua, Víctor; Grigoriev, Igor V. (Elsevier, 2016)
Plants and fungi use light and other signals to regulate development, growth, and metabolism. The fruiting bodies of the ...
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Nitric oxide in fungi: is there NO light at the end of the tunnel?

Cánovas López, David; Marcos, José F.; Marcos Rodríguez, Ana Teresa; Strauss, Joseph (Springer Verlag, 2016)
Nitric oxide (NO) is a remarkable gaseous molecule with multiple and important roles in different organisms, including ...
Patent. Invention
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Cepa microbiana Terribacillus SP-AE2B 122 con capacidad para llevar a cabo reacciones de transesterificación y usos de la misma

Escobar Niño, Almudena; Luna Martínez, Diego; Mellado Durán, María Encarnación; Cánovas López, David (Oficina Española de Patentes y Marcas , 2014)
Cepa Microbiana Terribacillus SP. AE2B 122 con capacidad para llevar a cabo reacciones de transesterificación y usos de ...
Article
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Selection and characterization of biofuel-producing environmental bacteria isolated from vegetable oil-rich wastes

Mellado Durán, María Encarnación; Cánovas López, David; Escobar Niño, Almudena; Luna, Carlos; Luna, Diego; Marcos Rodríguez, Ana Teresa (Public Library of Science, 2014)
Fossil fuels are consumed so rapidly that it is expected that the planet resources will be soon exhausted. Therefore, it ...
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Flow Cytometry of Microencapsulated Colonies for Genetics Analysis of Filamentous Fungi

Delgado Ramos, Lidia; Marcos Rodríguez, Ana Teresa; Ramos Guelfo, María Salud; Sánchez Barrionuevo, Leyre; Chávez de Diego, Sebastián; Cánovas López, David (Genetics Society of America:, 2014)
The analysis of filamentous fungi by flow cytometry has been impossible to date due to their filamentous nature and size. ...
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Cell-Type–Specific Transcriptional Profiles of the Dimorphic Pathogen Penicillium marneffei Reflect Distinct Reproductive, Morphological, and Environmental Demands

Pasricha, Shivani; Payne, Michael; Cánovas López, David; Pase, Luke; Ngaosuwankul, Nathamon (Genetics Society of America:, 2013)
Penicillium marneffei is an opportunistic human pathogen endemic to Southeast Asia. At 25° P. marneffei grows in a filamentous ...
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The fungal type II myosin in Penicillium marneffei, MyoB, is essential for chitin deposition at nascent septation sites but not actin localization

Cánovas López, David; J. Boyce, Kylie; Andrianopoulos, Alex (American Society for Microbiology, 2011)
Cytokinesis is essential for proliferative growth but also plays equally important roles during morphogenesis and development. ...
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Role of trehalose in growth at high temperature of Salmonella enterica serovar typhimurium

Cánovas López, David; Fletcher, Susanne A.; Hayashi, Mikachi; Csonka, Laszlo N. (American Society for Microbiology, 2001)
Moderate osmolality can stimulate bacterial growth at temperatures near the upper limit for growth. We investigated the ...
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Role of Nγ-acetyldiaminobutyrate as an enzyme stabilizer and an intermediate in the biosynthesis of hydroxyectoine

Nieto Gutiérrez, Joaquín José; Cánovas López, David; Borges, Nuno; Vargas Macías, Carmen; Ventosa Ucero, Antonio; Santos, Helena (American Society for Microbiology, 1999)
Strain CHR63 is a salt-sensitive mutant of the moderately halophilic wild-type strain Halomonas elongata DSM 3043 that is ...
PhD Thesis
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Bases moleculares de los mecanismos de osmorregulación en bacterias halófilas moderadas

Cánovas López, David; Nieto Gutiérrez, Joaquín José; Ventosa Ucero, Antonio; Vargas Macías, Carmen (1998)
Durante la última década, nuestro Equipo de Investigación ha realizado numerosos estudios encaminados a un mejor conocimiento ...
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Synthesis of glycine betaine from exogenous choline in the moderately halophilic bacterium Halomonas elongata

Nieto Gutiérrez, Joaquín José; Cánovas López, David; Vargas Macías, Carmen; Csonka, Laszlo N.; Ventosa Ucero, Antonio (American Society for Microbiology, 1998)
The role of choline in osmoprotection in the moderate halophile Halomonas elongata has been examined. Transport and ...
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Isolation and characterization of salt-sensitive mutants of the moderate halophile Halomonas elongata and cloning of the ectoine synthesis genes

Cánovas López, David; Vargas Macías, Carmen; Iglesias Guerra, Fernando; Csonka, Laszlo N.; Rhodes, David R.; Ventosa Ucero, Antonio; Nieto Gutiérrez, Joaquín José (American Society for Biochemistry and Molecular Biology Inc., 1997)
The moderate halophile Halomonas elongata Deustche Sommlung fur Mikroorganismen 3043 accumulated ectoine, hydroxyectoine, ...
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Osmoprotectants in Halomonas elongata: High-affinity betaine transport system and choline-betaine pathway

Nieto Gutiérrez, Joaquín José; Cánovas López, David; Vargas Macías, Carmen; Ventosa Ucero, Antonio; Csonka, Laszlo N. (American Society for Microbiology, 1996)
The osmoregulatory pathways of the moderately halophilic bacterium Halomonas elongata DSM 3043 have been investigated. ...