Medicina
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Artículo
Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry
(Ferrata Storti Foundation, 2024)Treatment options for patients with secondary acute myeloid leukemia (sAML) and AML with myeloid-related changes (AMLMRC) ...
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Oportunistic diagnosis based on age and hepatitis C virus clearance: an essential step to improve the overall health of the liver
(Aran Ediciones S.A., 2023)Back in January 2022, a The Lancet-European Association for the Study of the Liver (EASL) Commission on the impact of ...
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A phase IIa active-comparator-controlled study to evaluate the efficacy and safety of efinopegdutide in patients with non-alcoholic fatty liver disease
(Elsevier, 2023)Background & Aims: This study assessed the effects of the glucagon-like peptide-1 (GLP-1)/glucagon receptor ...
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Tesis Doctoral
Estudio de las características clínicas e histológicas y del manejo terapéutico del melanoma cutáneo primario en personas mayores en el área de gestión sanitaria sur de Sevilla
(2024-02-02)Introducción: El melanoma cutáneo es un tumor maligno cuya incidencia se ha ido incrementando en las últimas décadas a ...
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Tesis Doctoral
Enfermedad tromboembólica venosa en el paciente oncológico: manejo terapéutico y complicaciones
(2024-02-19)La relación entre la enfermedad tromboembólica venosa (ETV) y el cáncer representa un desafío en la práctica clínica. La ...
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Tesis Doctoral
Efecto de los antidiabéticos análogos del receptor de GLP1 sobre la distensibilidad vascular y la enfermedad cardiovascular en sujetos diabéticos tipo 2
(2024-02-21)Objetivos: analizar el comportamiento de los análogos del receptor de GLP1 (arGLP1) en sujetos diabéticos tras cumplir ...
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Clinical variables impacting on the estimation of utilities in chronic obstructive pulmonary disease
(Dove Medical Press LTD, 2015-02-16)Purpose: Health utilities are widely used in health economics as a measurement of an individual’s preference and show the ...
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Epidemiology and risk factors of mycotic aneurysm in patients with infective endocarditis and the impact of its rupture in outcomes. Analysis of a national prospective cohort
(Oxford Univ Press, 2024)Background. Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting
(Springer, 2018)Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic ...
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Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice
(MPDI, 2023-11-28)Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation ...
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Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring
(Frontiers Media S.A., 2024-01-16)Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and ...
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Hematological Neoplasms with Eosinophilia
(MDPI, 2024-01-12)The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
(Nature Publishing Group, 2024)BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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Tesis Doctoral
La melatonina como biomarcador de los trastornos del sueño en pacientes con Esclerosis Múltiple
(2023-09-28)Introducción: La EM se trata de una enfermedad inmunológica, inflamatoria desmielinizante y degenerativa del SNC, caracterizada ...
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Tesis Doctoral
Factores de riesgo para el desarrollo de infecciones por enterobacterales productores de carbapenemasas
(2024-01-17)INTRODUCCIÓN La resistencia a los antibióticos entre las bacterias ha sido reconocida como uno de los problemas de salud ...
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Predictors of mortality in solid organ transplant recipients with bloodstream infections due to carbapenemase-producing Enterobacterales: the impact of cytomegalovirus disease and lymphopenia
(BMC, 2020)Treatment of carbapenemase-producing Enterobacterales bloodstream infections in solid organ transplant recipients is ...
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Tesis Doctoral
Estudio de biomarcadores de neuroimagen multimodal implicados en la enfermedad de Parkinson
(2024-01-25)Las discinesias inducidas por levodopa (DILs) y el deterioro cognitivo constituyen unas de las manifestaciones clínicas ...
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Tesis Doctoral
Bacteriemias relacionadas con catéter tunelizado en pacientes en hemodiálisis: factores de riesgo, pronóstico y manejo clínico
(2024-01-10)Introducción. La bacteriemia relacionada con catéter tunelizado es una de las complicaciones más graves descritas entre ...
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Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry
(Nature Publishing Group, 2023)In 2020, the COVID-19 pandemic followed a two-wave pattern in most countries. Hospital admission for COVID-19 in one wave ...