Artículo
Human Long Telomeres and Epigenetic Marks
Autor/es | Vega Palas, Miguel Ángel
Vaquero Sedas, María Isabel |
Departamento | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular |
Fecha de publicación | 2013 |
Fecha de depósito | 2019-03-19 |
Publicado en |
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Resumen | We have read with interest the article “Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α” by Arnoult and colleagues [1]. This study focuses on human telomeric chromatin ... We have read with interest the article “Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α” by Arnoult and colleagues [1]. This study focuses on human telomeric chromatin structure using different techniques like Chromatin Immunoprecipitation (ChIP), cytolocalization or RT-qPCR. However, it has been performed without taking into consideration the presence of Interstitial Telomeric Sequences (ITSs) in the human genome. Some of the conclusions of the article are undoubtedly clear but there are others that might be explained in alternative ways, considering the existence of ITSs. Following, we mention some comments that arise from this interesting article. |
Cita | Vega Palas, M.Á. y Vaquero Sedas, M.I. (2013). Human Long Telomeres and Epigenetic Marks. CellBio, 2 (2), 70-72. |
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