Buscar
Mostrando ítems 1-3 de 3
Artículo
Apolar carbohydrates as DNA capping agents
(Royal Society of Chemistry, 2012)
Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. Here we present an apolar version of glucose and cellobiose as new capping agents that stack on ...
Artículo
In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations
(MDPI, 2020)
The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In some cases the drug is barely soluble; in others, the rapid transit of the formulation through ...
Artículo
Carbohydrate-DNA interactions at G-quadruplexes: Folding and stability changes by attaching sugars at the 5′-End
(Wiley-Blackwell, 2013)
Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry, ranging from chemical biology, supramolecular chemistry to nanoscience. We have prepared carbohydrate-DNA conjugates containing the ...