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Artículo
Porous titanium substrates coated with a bilayer of bioactive glasses
(Elsevier, 2020-09)
Porous titanium substrates coated by dripping-sedimentation technique with a novel bilayer of (45S5 / 1393) bioactive glasses are proposed to overcome some limitations of the use of titanium for implants, such as the stress ...
Artículo
Synthesis and deposition of silver nanoparticles on porous titanium substrates for biomedical applications
(Elsevier, 2021-01)
Ti implants are highly biocompatible and allow orderly bone growth but, unfortunately, in the first five years after implantation, 5–10% of them fail due to poor osseointegration and to the presence of bacterial infections ...
Artículo
Porous beta titanium alloy coated with a therapeutic biopolymeric composite to improve tribomechanical and biofunctional balance
(Elsevier, 2023-05)
Tooth loss is common in patients struggling with dental cavities, periodontal diseases, and tumors, as well as those who abuse tobacco or drugs. In this scenario, dental implants have become the primary treatment option ...
Artículo
GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery
(American Chemical Society, 2021)
The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged as new and exciting drug targets, due to their plausible translation from pharmacology to medicines. This perspective aims to report ...
Artículo
Versatile Biodegradable Poly(acrylic acid)-Based Hydrogels Infiltrated in Porous Titanium Implants to Improve the Biofunctional Performance
(American Chemical Society, 2023-09)
This research work proposes a synergistic approach to improve implants’ performance through the use of porous Ti substrates to reduce the mismatch between Young’s modulus of Ti (around 110 GPa) and the cortical bone ...
Artículo
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices
(Elsevier, 2022)
Chronic infection as a result of bacterial biofilm formation on implanted medical devices is a major global healthcare problem requiring new biocompatible, biofilm-resistant materials. Here we demonstrate how bespoke devices ...
Artículo
Influence of Femtosecond Laser Modification on Biomechanical and Biofunctional Behavior of Porous Titanium Substrates
(MDPI, 2022-04)
Bone resorption and inadequate osseointegration are considered the main problems of titanium implants. In this investigation, the texture and surface roughness of porous titanium samples obtained by the space holder technique ...
Artículo
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
(MDPI, 2020)
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic agents for magnetic hyperthermia and ...
Artículo
(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)
The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ((R)-8-OITC), present in watercress, based on the “DAG methodology” as well as to evaluate its ...
Artículo
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)
first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents—In Vitro Evaluation against Breast Cancer ...