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Mostrando ítems 1-10 de 22
Artículo
Reversible pH-sensitive chitosan-based hydrogels. Influence of dispersion composition on rheological properties and sustained drug delivery
(MDPI, 2018)
The present work deals with the synthesis of micro-structured biomaterials based on chitosan (CTS) for their applications as biocompatible carriers of drugs and bioactive compounds. Twelve dispersions were prepared by ...
Artículo
Hábitos y normas de seguridad recomendadas en un laboratorio de entorno químico
(Asociación Profesional de Gestores de Emergencias y Seguridad, 2008)
Las nuevas normativas que la Legislación impone relativas a los hábitos saludables y de seguridad que deben cumplirse en los laboratorios, han supuesto una revolución muy positiva en estos entornos de trabajo. Estos ...
Artículo
Tandem ATRP/Diels-Alder Synthesis of PolyHEMA-based Hydrogels
(Royal Society of Chemistry, 2014)
The efficient, controlled polymerization of a batch of new poly(hydroxyethyl methacrylate-co-furfuryl methacrylate)s, [poly(HEMA-co-FMA)], of various compositions was achieved using atom transfer radical polymerization ...
Artículo
Preparation of water-soluble glycopolymers derived from five-membered iminosugars
(Elsevier, 2019-10)
Iminosugars are carbohydrate mimetics that constitute the main group of oligosaccharide processing enzyme inhibitors. They play an important role in cell-cell recognition processes, thereby presenting a wide range ...
Artículo
Synthesis and Characterization of New Carbohydrate-based Polyureas
(Tech Science Press, 2013-07)
A batch of linear [m,n]-type sugar-based polyureas was synthesized by polyaddition reaction in solution from hexamethylene diisocyanate or 4,4’-methylene-bis(phenyl isocyanate) with the acyclic 2,3,4-tri-O-methyl-1,5- ...
Artículo
Synthetic Polymers from Sugar-Based Monomers
(American Chemical Society, 2016)
Artículo
pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems
(JSciMed Central, 2017-04)
Micelles are excellent devices to be used as controlled drug delivery systems since they exhibit the ability to protect the drug or encapsulated substance from the routes of degradation until they reach the site of action: ...
Artículo
Glucose-nucleobase pairs within DNA: Impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
(Royal Society of Chemistry, 2018)
Recently, we studied glucose-nucleobase pairs, a binding motif found in aminoglycoside-RNA recognition. DNA duplexes with glucose as a nucleobase were able to hybridize and were selective for purines. They were less stable ...
Artículo
Thiolated-polymer-based nanoparticles as an avant-garde approach for anticancer therapies—Reviewing thiomers from chitosan and hyaluronic acid
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Thiomers (or thiolated polymers) have broken through as avant-garde approaches in anticancer therapy. Their distinguished reactivity and properties, closely linked to their final applications, justify the extensive research ...
Artículo
Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine
(American Chemical Society, 2018-01-11)
Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The ...