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Artículo
Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)
Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related nausea and vomiting, have demonstrated that pharmacological inhibition of NK1R effectively reduces ...
Artículo
Antimicrobial Properties of Amino-Acid-Derived N-Heterocyclic Carbene Silver Complexes
(MDPI, 2022)
Complexes {Ag[NHCMes,R]}n (R = H, 2a; Me, 2b and 2b’; iPr, 2c; iBu, 2d), were prepared by treatment of imidazolium precursor compounds [ImMes,R] (2-(3-mesityl-1H-imidazol-3-ium-1-yl)acetate, 1a, (S)-2-alkyl(3-mesityl-1H- ...
Artículo
Microbiota-liver-bile salts axis, a novel mechanism involved in the contrasting effects of sodium selenite and selenium-nanoparticle supplementation on adipose tissue development in adolescent rats
(MDPI, 2023)
Adolescence is a period during which body composition changes deeply. Selenium (Se) is an excellent antioxidant trace element related to cell growth and endocrine function. In adolescent rats, low Se supplementation affects ...
Artículo
Different effects of low selenite and selenium-nanoparticle supplementation on adipose tissue function and insulin secretion in adolescent male rats
(MDPI, 2022)
Adolescence is a period of intense growth and endocrine changes, and obesity and insulin-resistance processes during this period have lately been rising. Selenium (Se) homeostasis is related to lipid metabolism depending ...