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Mostrando ítems 11-20 de 27
Artículo
Clickable iron oxide NPs based on catechol derived ligands: synthesis and characterization
(Taylor and Francis Group, 2020-03-05)
Clickable magnetic nanoparticles have attracted great attention as potential nanoplatforms for biomedical applications because of the high functionalization efficiency of their surfaces with biomolecules, which facilitates ...
Artículo
Synthesis and Characterization of New Biocompatible Amino Amphiphilic Compounds Derived from Oleic Acid as Nanovectors for Drug Delivery
(MDPI, 2019)
Amphiphilic molecules have been actively explored as promising materials in the field of bio and nanotechnology. These molecules are constituted by a polar head and a lipophilic tail and in an aqueous medium are self-assemble ...
Artículo
Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)
Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related nausea and vomiting, have demonstrated that pharmacological inhibition of NK1R effectively reduces ...
Artículo
Tailoring carbon nanotube surfaces with glyconanorings: New bionanomaterials with specific lectin affinity
(Royal Society of Chemistry, 2009)
Remarkably stable, water-soluble glyconanoring-coated SWCNTs were prepared by self organization and photopolymerization of neutral diacetylene-based glycolipids on the nanotube surface; the nanoconstructs are able to engage ...
Artículo
Synthesis and characterization of enantiopure chiral NH2/SO palladium complexes
(Royal Society of Chemistry, 2023)
A series of enantiopure chiral NH2/SO palladium complexes have been synthesised with high yields by treating the corresponding tert-butylsulfinamide/sulfoxide derivatives with Pd(CH3CN)2Cl2. The enantiopure chiral ligands ...
Artículo
Chiral sulfur derivatives in the allylation of acyl hydrazones: C 2-symmetric bis-sulfinamides as enhanced chiral organic promoters
(Royal Society of Chemistry, 2010-10)
Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl hydrazones, the nature of the spacer and the substituent at the sulfinyl sulfur are key elements for the ...
Artículo
Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines
(American Chemical Society, 2016-07)
A new type of chiral sulfinamide phosphinate catalysts with up to three stereogenic centers, readily accessible from commercially available starting materials, is reported. The naphthyl derivative SulPhos proved to be ...
Artículo
Immunomodulatory Effects of (R)-Sulforaphane on LPS-Activated Murine Immune Cells: Molecular Signaling Pathways and Epigenetic Changes in Histone Markers
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The aim of this study was to explore the immunomodulatory effects of the natural enantiomer (R)-Sulforaphane (SFN) and the possible signaling pathways involved in an ex vivo model of LPS-stimulated murine peritoneal ...
Artículo
Synthesis of 1D-glyconanomaterials by a hybrid noncovalent–covalent functionalization of single wall carbon nanotubes: a study of their selective interactions with lectins and with live cells
(Royal Society of Chemistry, 2015)
To take full advantage of the remarkable applications of carbon nanotubes in different fields, there is a need to develop effective methods to improve their water dispersion and biocompatibility while maintain- ing their ...
Artículo
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)
A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide NK1 receptor ligands by a one-pot cascade process. Their biological effects via interaction with ...