Buscar
Mostrando ítems 21-30 de 80
Artículo
Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices
(Wiley-Blackwell, 2021)
As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step change in the personalization of medical devices it is shown ...
Artículo
Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme
(Elsevier, 2022)
The stereoselective addition of ethyl acetate enolate to the C═N bond of N-tert-butylsulfinylimines has been investigated in depth. A significant effect of the LHMDS amount and the N-sulfinylimine nature on the stereoselectivity ...
Artículo
Biofunctionalization of Porous Ti Substrates Coated with Ag Nanoparticles for Potential Antibacterial Behavior
(MDPI, 2021-04)
Ti prosthesis have shown better biological compatibility, mechanical performance, and resistance to corrosion in cases of bone replacements. Nevertheless, fully dense Ti in connection with bone-host tissues show stress-shielding ...
Artículo
Inhibition of Endothelial Inflammatory Response by HT-C6, a Hydroxytyrosol Alkyl Ether Derivative
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Hydroxytyrosol (HT) is a bioactive phenolic compound naturally present in olives and extra virgin olive oil (EVOO) which is described as an antioxidant, antitumoral and antiangiogenic molecule. Previous studies of ...
Artículo
Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol
(Elsevier, 2021)
Nowadays there is not an effective drug for the treatment of infections caused by human adenovirus (HAdV) which supposes a clinical challenge, especially for paediatric and immunosuppressed patients. Here, we describe the ...
Tesis Doctoral
Drug Encapsulation and Controlled Release Via Stimuli Responsive Nano and Micro Structured Polymeric Materials
(2020-05-21)
Life expectancy in Andalusia and in Spain has grown steadily over the past 20 years and, in 2017, they were around 86 and 80 years for women and men, respectively. This trend is the same as that observed in other developed ...
Artículo
Applications and multidisciplinary perspective on 3D printing techniques: Recent developments and future trends
(Elsevier, 2023-12)
n industries as diverse as automotive, aerospace, medical, energy, construction, electronics, and food, the engineering technology known as 3D printing or additive manufacturing facilitates the fabrication of rapid prototypes ...
Artículo
Artículo
Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes
(MDPI, 2020)
Labdane diterpenes are widespread classes of natural compounds present in variety of marine and terrestrial organisms and plants. Many of them represents “natural libraries” of compounds with interesting biological activities ...
Artículo
PEGylated Terbium-Based Nanorods as Multimodal Bioimaging Contrast Agents
(American Chemical Society, 2021)
Diagnostic imaging strongly relies on the use of contrast agents (CAs). In general terms, current CAs present undesirable side effects that encourage researchers and pharmaceutical companies to continually search for safer ...