Listar Artículos (Química Orgánica) por título
Mostrando ítems 125-144 de 247
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Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases
(Wiley-Blackwell, 2017)Novel pyrrolidine-based multivalent iminosugars, synthesized by a CuAAC approach, have shown remarkable multivalent effects ...
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Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance
(Elsevier, 2021)Drug resistance remains the major cause of cancer treatment failure especially at the late stage of the disease. However, ...
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Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
(Future Medicine Ltd., 2017)Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient ...
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Molecular Recognition of Natural and Non-Natural Substrates by Cellodextrin Phosphorylase from Ruminiclostridium Thermocellum Investigated by NMR Spectroscopy
(Wiley-Blackwell, 2021)β-1→4-Glucan polysaccharides like cellulose, derivatives and analogues, are attracting attention due to their unique ...
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Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds
(Schweizerische Chemische Gesellschaft, 2011)We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.
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Multienzymatic processes involving baeyer–villiger monooxygenases
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Baeyer–Villiger monooxygenases (BVMOs) are flavin-dependent oxidative enzymes capable of catalyzing the insertion of an ...
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Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide
(Frontiers Media S.A., 2021)Biofilms confine bacterial cells within self-produced matrices, offering advantages such as protection from antibiotics ...
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Multiply–linked cyclodextrin–aromatic hybrids: Caps, hinges and clips
(Taylor & Francis, 2019)The judicious combination of shaping and recognition elements in cage-type architectures represents a powerful strategy ...
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Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators
(Royal Society of Chemistry, 2019)Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide ...
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N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study
(Elsevier, 2020-05)Our goal was the evaluation of a series of N-1,2,3-triazole-isatin derivatives for multi-target activity which included ...
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N-Heterotricyclic Cationic Carbene Ligands. Synthesis, Reactivity and Coordination Chemistry
(Royal Society of Chemistry, 2018)The direct dialkylation of triazolo[4,3-b]isoquinolin-3-ylidene structures readily affords dicationic N-heterotricyclic ...
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Nanoparticle-delivered HIV peptides to dendritic cells a promising approach to generate a therapeutic vaccine
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Finding a functional cure for HIV-1 infection will markedly decrease the social and economic burden of this disease. In ...
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New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells
(Public Library of Science, 2013)sp2-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on ...
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New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
(Elsevier, 2017)We have designed a series of tacrine-based homo- and heterodimers that incorporate an antioxidant tether (selenoureido, ...
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NleB/SseK-catalyzed arginine-glycosylation and enteropathogen virulence are finely tuned by a single variable position contiguous to the catalytic machinery
(Royal Society of Chemistry, 2021)NleB/SseK effectors are arginine-GlcNAc-transferases expressed by enteric bacterial pathogens that modify host cell proteins ...
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Nodulation-gene-inducing flavonoids increase overall production of autoinducers and expression of N-acyl homoserine lactone synthesis genes in rhizobia
(2011)Legume-nodulating rhizobia use N-acyl homoserine lactones (AHLs) to regulate several physiological traits related to the ...
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NolR Regulates Diverse Symbiotic Signals of Sinorhizobium fredii HH103
(The American Phytopathological Society, 2004)We have investigated in Sinorhizobium fredii HH103-1 (=HH103 Strr ) the influence of the nolR gene on the production of ...
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Non-Ionic Osmotic Stress Induces the Biosynthesis of Nodulation Factors and Affects Other Symbiotic Traits in Sinorhizobium fredii HH103
(MDPI, 2023)Simple Summary: Rhizobia are soil proteobacteria able to establish nitrogen-fixing symbiosis with host legumes. This ...