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Artículo
Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa
Delgado Valverde, María Mercedes; Portillo Calderón, Inés María; Alcalde Rico, Manuel; Conejo Gonzalo, Mª Carmen; Hidalgo, Carmen; Del Toro Esperón, Carlos; Pascual Hernández, Álvaro (Springer, 2023-12-29)Purpose: Relebactam is a novel β-lactamase inhibitor, which, when combined with imipenem/cilastatin, is active against ...
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Artículo
Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli
Portillo Calderón, Inés María; Ortiz Padilla, Miriam; Rodríguez Martínez, José Manuel; De Gregorio Iaria, Belén; Blázquez, Jesús; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (Oxford University Press, 2020)Objectives: To explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant ...
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Artículo
Effect of Glycerol on Fosfomycin Activity against Escherichia coli
Ortiz Padilla, Miriam; Portillo Calderón, Inés María; Velázquez Escudero, Ana; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel; Docobo Pérez, Fernando (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Fosfomycin is an antimicrobial that inhibits the biosynthesis of peptidoglycan by entering the bacteria through two channels ...
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Tesis Doctoral
Heterorresistencia a fosfomicina en Escherichia coli: bases moleculares y efecto en su potencial terapéutico
Portillo Calderón, Inés María (2022-03-15)En las últimas décadas, el aumento progresivo de la resistencia a los antimicrobianos se ha convertido en un problema ...
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Artículo
Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain
Pérez Palacios, Patricia; Gual de Torrella, Ana; Portillo Calderón, Inés María; Recacha Villamor, Esther; Franco Álvarez de Luna, Francisco; López Cerero, Lorena; Pascual Hernández, Álvaro (Multidisciplinary Digital Publishing Institute (MDPI), 2023)In 2014–2015, the main CTX-M-15- and OXA-48-producing clone in our region was ST15. Recently, K. pneumoniae ST15 isolates ...