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Listar por autor "Pérez Ortín, José E."
Mostrando ítems 1-6 de 6
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Artículo
Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast
Medina, Daniel A.; Jordán Pla, Antonio; Millán Zambrano, Gonzalo; Chávez de Diego, Sebastián; Pérez Ortín, José E. (Frontiers Media, 2014)The 5′ to 3′ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component ...
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Artículo
Growth rate controls mRNA turnover in steady and non-steady states
García Martínez, José; Troulé, K.; Chávez de Diego, Sebastián; Pérez Ortín, José E. (Taylor & Francis, 2016)Gene expression has been investigated in relation with growth rate in the yeast Saccharomyces cerevisiae, following different ...
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Artículo
Regulon-Specific Control of Transcription Elongation across the Yeast Genome
Pelechano, Vicent; Jimeno González, Silvia; Rodríguez Gil, Alfonso; García Martínez, José; Pérez Ortín, José E.; Chávez de Diego, Sebastián (Public Library of Science, 2009)Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide ...
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Artículo
Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning
Gutiérrez Pozo, Gabriel; Millán Zambrano, Gonzalo; Medina, Daniel A.; Jordán Pla, Antonio; Pérez Ortín, José E.; Peñate Salas, Xenia; Chávez de Diego, Sebastián (BioMed Central, 2017)TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the ...
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Artículo
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons
García Martínez, José; Delgado Ramos, Lidia; Ayala, Guillermo; Pelechano, Vicent; Andrés León, Eduardo; Chávez de Diego, Sebastián; Pérez Ortín, José E. (Oxford University Press, 2016)We analyzed 80 different genomic experiments, and found a positive correlation between both RNA polymerase II transcription ...
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Artículo
The Total mRNA Concentration Buffering System in Yeast is Global Rather than Gene-specific
García Martínez, José; Medina, Daniel A.; Bellvís, P.; Sun, M.; Cramer, P.; Chávez de Diego, Sebastián; Pérez Ortín, José E. (Cold Spring Harbor Laboratory Press, 2021)Gene expression in eukaryotes does not follow a linear process from transcription to translation and mRNA degradation. ...