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Listar por autor "Muñoz Galván, Sandra"
Mostrando ítems 1-11 de 11
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Artículo
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Muñoz Galván, Sandra; García Rubio, María Luisa; Ortega Moreno, Pedro; Ruiz Pérez, José Francisco; Jimeno González, Sonia; Pardo, Benjamín; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017)Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
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Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells
García Heredia, José Manuel; Otero Albiol, Daniel; Pérez, Marco; Pérez Castejón, Elena; Muñoz Galván, Sandra; Carnero, Amancio (Springer Nature, 2020)MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a broad range of carcinomas. ...
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Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
Muñoz Galván, Sandra; López Saavedra, Ana; Jackson, Stephen P.; Huertas Sánchez, Pablo; Cortés Ledesma, Felipe; Aguilera López, Andrés (Oxford University Press, 2013)While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of ...
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Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer
Verdugo Sivianes, Eva María; Navas, Lola; Molina Pinelo, Sonia; Quintanal Villalonga, Álvaro Diego; García Heredia, José Manuel; Felipe Abrio, Blanca; Muñoz Galván, Sandra (Impact Journals, 2017)The scaffold protein Spinophilin (Spinophilin, PPP1R9B) is one of the regulatory subunits of phosphatase-1 (PP1), directing ...
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Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange
Muñoz Galván, Sandra; Tous, Cristina; Blanco, Miguel G.; Schwartz, Erin K.; Ehmsen, Kirk T.; West, Stephen C.; Heyer, Wolf-Dietrich; Aguilera López, Andrés (2012)Most spontaneous DNA double-strand breaks (DSBs) arise during replication and are repaired by homologous recombination ...
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Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid
Muñoz Galván, Sandra; Jimeno González, Sonia; Rothstein, Rodney; Aguilera López, Andrés (Public Library of Science, 2013)DNA double-strand breaks (DSBs) are harmful lesions that arise mainly during replication. The choice of the sister chromatid ...
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MAP17 (PDZK1IP1) and pH2AX are potential predictive biomarkers for rectal cancer treatment efficacy
Peinado Serrano, Javier; Muñoz Galván, Sandra; Espinosa Sánchez, Asunción; Suárez Martínez, Elisa; Felipe Abrio, Blanca; Fernández Fernández, María del Carmen; Carnero Moya, Amancio (Impact Journals, 2018)Rectal cancer represents approximately 10% of cancers worldwide. Preoperative chemoradiotherapy increases complete pathologic ...
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New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools
Muñoz Galván, Sandra; Felipe Abrio, Blanca; García Carrasco, Miguel; Domínguez Piñol, Julia; Suarez Martínez, Elisa; Verdugo Sivianes, Eva María; Espinosa Sánchez, Asunción; Navas Maldonado, Lola Eufemia; Otero Abiol, Daniel; García Heredia, José Manuel; Carnero Moya, Amancio (BMC, 2019)BACKGROUND: Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and ...
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PAI1 is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment with PIM Inhibitor AZD1208
Muñoz Galván, Sandra; Rivero, María; Peinado Serrano, Javier; Martinez Pérez, Julia; Fernández Fernández, María del Carmen; Ortiz, María José; García Heredia, José Manuel; Carnero Moya, Amancio (MDPI, 2020)Colorectal cancer (CRC) is the third most common cancer worldwide. The standard treatment in locally advanced rectal cancer ...
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Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment
Pérez, Marco; García Heredia, José Manuel; Felipe Abrio, Blanca; Muñoz Galván, Sandra; Martín Broto, Javier; Carnero Moya, Amancio (Springer Nature, 2020)Sarcomas constitute a rare heterogeneous group of tumors, including a wide variety of histological subtypes. Despite ...
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The Rad50 coiled-coil domain is indispensable for Mre11 complex functions
Hohl, Marcel; Muñoz Galván, Sandra; Tous Rivera, Cristina; Aguilera López, Andrés; Petrini, John H. J. (Nature Publishing Group, 2011)The Mre11 complex (Mre11, Rad50 and Xrs2 in Saccharomyces cerevisiae) influences diverse functions in the DNA damage ...