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Listar por autor "Morcuende Fernández, Sara R."
Mostrando ítems 1-16 de 16
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Artículo
Complementary Actions of BDNF and Neurotrophin-3 on the Firing Patterns and Synaptic Composition of Motoneurons
Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Tena, Juan J.; Benítez Temiño, Beatriz; Pecero, María L.; Morcuende Fernández, Sara R.; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Society for Neuroscience, 2009)Neurotrophins, as target-derived factors, are essential for neuronal survival during development, but during adulthood, ...
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Artículo
Differential regulation of the expression of neurotrophin receptors in rat extraocular motoneurons after lesion
Morcuende Fernández, Sara R.; Rodríguez Matarredona, Esperanza; Benítez Temiño, Beatriz; Muñoz Hernández, Rocío; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Wiley, 2011)Neurotrophins acting through high-affinity tyrosine kinase receptors (trkA, trkB, and trkC) play a crucial role in regulating ...
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Artículo
Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons
Silva Hucha, Silvia; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María; Morcuende Fernández, Sara R.; García Hernández, Rosendo Miguel (Public Library of Science, 2017)Recent studies show a relationship between the deficit of vascular endothelial growth factor (VEGF) and motoneuronal ...
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Artículo
Extraocular Motor System Exhibits a Higher Expression of Neurotrophins When Compared with Other Brainstem Motor Systems
García Hernández, Rosendo Miguel; Silva Hucha, Silvia; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; Benítez Temiño, Beatriz (Frontiers Media, 2017)Extraocular motoneurons resist degeneration in diseases such as amyotrophic lateral sclerosis. The main objective of the ...
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Tesis Doctoral
Factor de crecimiento del endotelio vascular (VEGF) en el sistema oculomotor: presencia y modulación tras la lesión
Silva Hucha, Silvia (2020-01-17)Estudios previos han demostrado que las motoneuronas que inervan los músculos extraoculares muestran una menor vulnerabilidad ...
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Artículo
Functional Diversity of Neurotrophin Actions on the Oculomotor System
Benítez Temiño, Beatriz; Davis López de Carrizosa, María América; Morcuende Fernández, Sara R.; Rodríguez Matarredona, Esperanza; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (MDPI AG, 2016)Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance ...
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Artículo
Nerve Growth Factor Regulates the Firing Patterns and Synaptic Composition of Motoneurons
Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2010)Target-derived neurotrophins exert powerful synaptotrophic actions in the adult brain and are involved in the regulation ...
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Artículo
Neural Progenitor Cell Implants in the Lesioned Medial Longitudinal Fascicle of Adult Cats Regulate Synaptic Composition and Firing Properties of Abducens Internuclear Neurons
Morado Díaz, Camilo José; Rodríguez Matarredona, Esperanza; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2014)Transplants of neural progenitor cells (NPCs) into the injured CNS have been proposed as a powerful tool for brain repair, ...
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Trabajo Fin de Grado
Neurogénesis en el cerebro adulto
Villar Leveque, Laura (2022)En los años 60 se encontraron por primera vez evidencias que apoyaban la formación de nuevas neuronas en el cerebro adulto ...
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Artículo
Neuronal Premotor Networks Involved in Eyelid Responses: Retrograde Transneuronal Tracing with Rabies Virus from the Orbicularis Oculi Muscle in the Rat
Morcuende Fernández, Sara R.; Delgado García, José María; Ugolini, Gabriella (Society for Neuroscience, 2002)Retrograde transneuronal tracing with rabies virus from the right orbicularis oculi muscle was used to identify neural ...
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Artículo
Neuroprotective Effect of Vascular Endothelial Growth Factor on Motoneurons of the Oculomotor System
Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (MDPI, 2021-01)Vascular endothelial growth factor (VEGF) was initially characterized as a potent angiogenic factor based on its activity ...
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Artículo
Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro
Herrera Lira, Alejandro; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza (MDPI, 2021)Neural progenitor cells (NPCs) are self-renewing and multipotent cells that persist in the postnatal and adult brain in ...
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Artículo
Sources and lesion-induced changes of VEGF expression in brainstem motoneurons
Silva Hucha, Silvia; Carrero Rojas, Génova; Fernández de Sevilla, María Estrella; Benítez Temiño, Beatriz; Davis López de Carrizosa, María América; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (Springer Nature, 2020-04-01)Motoneurons of the oculomotor system show lesser vulnerability to neurodegeneration compared to other cranial motoneurons, ...
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Artículo
To Become or Not to Become Tumorigenic: Subventricular Zone Versus Hippocampal Neural Stem Cells
Fontán Lozano, Ángela del Carmen; Morcuende Fernández, Sara R.; Davis López de Carrizosa, María América; Benítez Temiño, Beatriz; Mejías Estévez, Rebeca María; Rodríguez Matarredona, Esperanza (Frontiers Media S.A., 2020)Neural stem cells (NSCs) persist in the adult mammalian brain in two neurogenic regions: the subventricular zone lining ...
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Artículo
Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat
Acosta, Lourdes; Morcuende Fernández, Sara R.; Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Frontiers Media, 2018)Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, ...
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Artículo
VEGF expression disparities in brainstem motor neurons of the SOD1GP3A ALS model: Correlations with neuronal vulnerability
Silva-Hucha, Silvia; Fernandez de Sevilla, Estrella M.; Humphreys, Kirsty M.; Benson, Fiona E.; Franco, Jaime M.; Pozo Pérez, David; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (Elsevier, 2024)Amyotrophic lateral sclerosis (ALS) is a rare neuromuscular disease characterized by severe muscle weakness mainly due ...