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Listar por autor "Lucena Cacace, Antonio"
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Tesis Doctoral
Caracterización del gen Nampt en el proceso de patogénesis tumoral, valoración diagnóstica, pronóstica y como diana terapeútica.
Lucena Cacace, Antonio (2017-12-04)El cáncer es una enfermedad genética compleja donde el metabolismo juega un papel fundamental. Las reacciones de ...
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Artículo
Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.
Perez, Marco; Lucena Cacace, Antonio; Marín Gómez, Luis Miguel; Padillo Ruiz, Francisco Javier; Robles Frias, MJ; Saez, Carmen; García Carbonero, Rocío; Carnero Moya, Amancio (Impact Journals, 2016-04-20)Despite the development of new antineoplastic agents for the treatment of colorectal cancer (CRC), oxaliplatin and ...
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Artículo
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy
García Heredia, José Manuel; Verdugo Sivianes, Eva María; Lucena Cacace, Antonio; Molina Pinelo, Sonia; Carnero Moya, Amancio (Impact Journals, 2016)NumbL, or Numb-like, is a close homologue of Numb, and is part of an evolutionary conserved protein family implicated in ...
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Artículo
The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB
García Heredia, José Manuel; Lucena Cacace, Antonio; Verdugo Sivianes, Eva María; Pérez, Marco; Carnero Moya, Amancio (American Association for Cancer Research, 2017)Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor ...