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Listar por autor "González Aguilera, Cristina"
Mostrando ítems 1-10 de 10
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Artículo
A genome-wide function of THSC/TREX-2 at active genes prevents transcription–replication collisions
Santos Pereira, José María; García Rubio, María Luisa; González Aguilera, Cristina; Luna Varo, Rosa María; Aguilera López, Andrés (Oxford University Press, 2014)The THSC/TREX-2 complex of Saccharomyces cerevisiae mediates the anchoring of transcribed genes to the nuclear pore, linking ...
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Efficacy of Eribulin Plus Gemcitabine Combination in L-Sarcomas
López Álvarez, María; González Aguilera, Cristina; Moura, David S.; Sánchez Bustos, Paloma; Mondaza Hernández, José L.; Martín Ruiz, Marta; Renshaw, Marta; Ramos, Rafael; Castilla, Carolina; Blanco Alcaina, Elena; Hindi, Nadia; Martín Broto, Javier (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Although the overall survival of advanced soft-tissue sarcoma (STS) patients has increased in recent years, the median ...
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Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair
Gaillard, Hélène; Tous Rivera, Cristina; Botet, Javier; González Aguilera, Cristina; Quintero, María José; Viladevall, Laia; García Rubio, María Luisa; Rodríguez Gil, Alfonso; Marín, Antonio; Ariño, Joaquín; Revuelta, José Luis; Chávez de Diego, Sebastián; Aguilera López, Andrés (Public Library of Science, 2009)RNA polymerases frequently deal with a number of obstacles during transcription elongation that need to be removed for ...
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Nab2 functions in the metabolism of RNA driven by polymerases II and III
González Aguilera, Cristina; Tous, Cristina; Babiano González, Reyes; Cruz Díaz, Jesús de la; Luna Varo, Rosa María; Aguilera López, Andrés (American Society for Cell Biology, 2011)Gene expression in eukaryotes is an essential process that includes transcription, RNA processing, and export. One ...
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New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation
Jimeno González, Sonia; Tous Rivera, Cristina; García Rubio, María Luisa; Ranes, Michael; González Aguilera, Cristina; Marín Rodríguez, Antonio; Aguilera López, Andrés (American Society for Microbiology, 2011)Formation of a ribonucleoprotein particle (mRNP) competent for export requires the coupling of transcription with mRNA ...
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Repeat RNAs associate with replication forks and post-replicative DNA
Gylling, Helene M.; González Aguilera, Cristina; Smith, Martin A.; Kaczorowski, Dominik C.; Groth, Anja; Lund, Anders H. (Cold Spring Harbor Laboratory Press, 2020)Noncoding RNA has a proven ability to direct and regulate chromatin modifications by acting as scaffolds between DNA and ...
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Artículo
Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease
López Jiménez, Elena; González Aguilera, Cristina (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Chromatin organization is essential to maintain a correct regulation of gene expression and establish cell identity. ...
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Artículo
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
Boulos Faza, Marius; Kemmler, Stefan; Jimeno González, Sonia; González Aguilera, Cristina; Aguilera López, Andrés; Hurt, E (Rockefeller University Press, 2009)The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in ...
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The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability
González Aguilera, Cristina; Tous Rivera, Cristina; Gómez González, Belén; Huertas Sánchez, Pablo; Luna Varo, Rosa María; Aguilera López, Andrés (American Society for Cell Biology, 2008)The eukaryotic THO/TREX complex, involved in mRNP biogenesis, plays a key role in the maintenance of genome integrity in ...
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Transcription at the proximity of the nuclear pore: A role for the THP1-SAC3-SUS1-CDC31 (THSC) complex
Luna Varo, Rosa María; González Aguilera, Cristina; Aguilera López, Andrés (Landes Bioscience, 2009)A key aspect of eukaryotic gene expression is the coupling of transcription with RNA processing, polyadenylation and export. ...