- idUS
- Listar por autor
Listar por autor "Cruz Merino, Luis de la"
Mostrando ítems 1-20 de 73
-
Artículo
2018 consensus statement by the Spanish Society of Pathology and the Spanish Society of Medical Oncology on the diagnosis and treatment of cancer of unknown primary
Losa, F.; Iglesias, L.; Pane, M.; Sanz, J.; Nieto, B.; Fuste, V.; Cruz Merino, Luis de la; Concha, A.; Balana, C.; Matias-Guiu, X. (Springer, 2018)Cancer of unknown primary (CUP) is defned as a heterogeneous group of tumours that present with metastasis, and in which ...
-
Artículo
5-year outcomes with cobimetinib plus vemurafenib in BRAFV600 mutation⇓positive advanced melanoma: extended follow-up of the coBRIM study
Ascierto, Paolo Antonio; Dreno, Brigitte; Larkin, James; Ribas, Antoni; Cruz Merino, Luis de la; McArthur, Grant A. (American Association for Cancer Research, 2021)Purpose: The randomized phase III coBRIM study (NCT01689519) demonstrated improved progression-free survival (PFS) and ...
-
Artículo
A genetic profling guideline to support diagnosis and clinical management of lymphomas
Sánchez Beato, Margarita; Méndez, Miriam; Criado Guirado, María José; Pedrosa, Lucía; Sequero, Silvia; Yanguas-Casás, Natalia; Cruz Merino, Luis de la; Gálvez, Laura; Llanos, Marta; García, Juan Fernando; Provencio, Mariano (Springer Nature, 2023)The new lymphoma classifcations (International Consensus Classifcation of Mature Lymphoid Neoplasms, and 5th World Health ...
-
Artículo
Adjuvant nivolumab for stage III/IV melanoma: evaluation of safety outcomes and association with recurrence-free survival
Mandala, Mario; Larkin, James R.; Ascierto, Paolo Antonio; Del Vecchio, Michele; Gogas, Helen; Cruz Merino, Luis de la; Weber, Jeffrey; Lobo, Maurice (BMJ Publishing Group, 2021-08-21)Background Several therapeutic options are now available in the adjuvant melanoma setting, mandating an understanding ...
-
Artículo
Adjuvant nivolumab versus ipilimumab (CheckMate 238 trial): Reassessment of 4-year efficacy outcomes in patients with stage III melanoma per AJCC-8 staging criteria
Larkin, James; Weber, Jeffrey; Del Vecchio, Michele; Gogas, Helen; Arance, Ana M.; Dalle, Stephane; Cruz Merino, Luis de la; Mandalá, Mario (Elsevier Science Ltd, 2022)Abstract Purpose: Nivolumab was approved as adjuvant therapy for melanoma based on data from CheckMate 238, which enrolled ...
-
Artículo
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III/IV Melanoma: 5-Year Efficacy and Biomarker Results from CheckMate 238
Larkin, James; Del Vecchio, Michele; Mandalá, Mario; Gogas, Helen; Arance Fernandez, Ana M.; Dalle, Stéphane; Cruz Merino, Luis de la; Weber, Jeffrey (American Association Cancer Research, 2023)lumab significantly improved recurrence-free survival (RFS) and distant metastasis-free survival versus ipilimumab in ...
-
Artículo
Adjuvant pembrolizumab versus placebo in resected high risk stage II melanoma: Health-related quality of life from the randomized phase 3 KEYNOTE-716 study
Khattak, Muhammad A.; Luke, Jason J.; Long, Georgina V.; Ascierto, Paolo A.; Rutkowski, Piotr; Schadendorf, Dirk; Cruz Merino, Luis de la; Kirkwood, John M. (Elsevier Science Ltd, 2022)Abstract Background: Adjuvant pembrolizumab significantly improved recurrence-free survival (RFS) versus placebo in ...
-
Artículo
Adjuvant Therapy of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Patients With Resected Stage IIIB-D or Stage IV Melanoma (CheckMate 915)
Weber, Jeffrey S.; Schadendorf, Dirk; Del Vecchio, Michele; Larkin, James; Atkinson, Victoria; Schenker, Michael; Cruz Merino, Luis de la; Long, Georgina V. (American Society of Clinical Oncology, 2023)PURPOSE Ipilimumab and nivolumab have each shown treatment benefit for high-risk resected melanoma. The phase III CheckMate ...
-
Tesis Doctoral
Análisis del perfil de respuesta inmune en sangre periférica inducido por tratamiento sistémico en el carcinoma de mama avanzado
Sánchez León, María Luisa (2021-06-09)La identificación de los diferentes elementos que intervienen en el proceso de inmunoedición, parece clave para explicar ...
-
Artículo
BERENICE Final Analysis: Cardiac Safety Study of Neoadjuvant Pertuzumab, Trastuzumab, and Chemotherapy Followed by Adjuvant Pertuzumab and Trastuzumab in HER2-Positive Early Breast Cancer
Dang, Chau; Ewer, Michael S.; Delaloge, Suzette; Ferrero, Jean-Marc; Colomer, Ramon; Cruz Merino, Luis de la; Swain, Sandra M. (MDPI, 2022)BERENICE (NCT02132949) assessed the cardiac safety of the neoadjuvant–adjuvant pertuzumab–trastuzumab-based therapy for ...
-
Artículo
Cancer nano-immunotherapy: the novel and promising weapon to fight cancer
García-Domínguez, Daniel J.; López Enriquez, Soledad; Alba Jiménez, Gonzalo; Garnacho Montero, Carmen; Jiménez Cortegana, Carlos; Flores-Campos, Rocío; Cruz Merino, Luis de la; Hajji, Nabil; Sánchez Margalet, Víctor; Hontecillas-Prieto, Lourdes (Mdpi Ag, 2024)Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until ...
-
Tesis Doctoral
Caracterización del perfil inmunitario en sangre periférica y en tejido de carcinoma de mama con tratamiento neoadyuvante. Estudio de su potencial papel pronóstico y predictivo de respuesta
Palazón Carrión, Natalia (2020-01-16)Introducción: Los estudios traslacionales permiten una correcta interrelación entre la investigación básica y la clínica. ...
-
Artículo
Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer
Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez-León, M. Luisa; Henao Carrasco, Fernando Manuel; Nogales-Fernández, Esteban; Chiesa, Massimo; Caballero, Rosalía; Rojo, Federico; Nieto García, María Adoración; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (Nature publishing group, 2021)Identifcation of the diferent elements intervening at the tumor microenvironment seems key to explain clinical evolution ...
-
Artículo
Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer
Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez León, María Luisa; Nieto García, María Adoración; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (Nature Publishing Group, 2021-07-13)Identification of the different elements intervening at the tumor microenvironment seems key to explain clinical evolution ...
-
Artículo
Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
Jiménez Cortegana, Carlos; Palazón Carrión, Natalia; Martín García-Sancho, Alejandro; Nogales-Fernández, Esteban; Carnicero-González, Fernando; Ríos Herranz, Eduardo; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (BMJ, 2021)Background The search for immunological markers with ability of predicting clinical outcome is a priority in lymphomas, ...
-
Artículo
Circulating myeloid-derived suppressor cells may be a useful biomarker in the follow-up of unvaccinated COVID-19 patients after hospitalization
Jiménez Cortegana, Carlos; Salamanca, Elena; Palazón Carrión, Natalia; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Vilariño García, Teresa; Gutiérrez Gutiérrez, Belén; Garnacho Montero, José; Cruz Merino, Luis de la; Rodríguez-Baño, Jesús; Sánchez Margalet, Víctor (Frontiers Media S.A., 2023)SARS-CoV-2 infection is the cause of the disease named COVID-19, a major public health challenge worldwide. Differences ...
-
Artículo
Circulating regulatory T cells from breast cancer patients in response to neoadjuvant chemotherapy
Sánchez Margalet, Víctor; Barco Sánchez, Antonio; Vilariño García, Teresa; Jiménez Cortegana, Carlos; Pérez Pérez, Antonio; Henao Carrasco, Fernando Manuel; Lobo Acosta, María Ángeles; Cruz Merino, Luis de la (Amer Publ Co, 2019)Background: Immune escape of tumor cells is a new hallmark of cancer in general, and breast cancer, in particular. ...
-
Artículo
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF‑mutated melanoma treated in the randomized coBRIM study
Cruz Merino, Luis de la; Di Guardo, Lorenza; Grob, Jean Jacques; Venosa, Alfredo; Larkin, James; McArthur, Grant A.; Dreno, Brigitte (Biomed Central LTD, 2017)Background: Serous chorioretinopathy has been associated with MEK inhibitors, including cobimetinib. We describe the ...
-
Artículo
Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells
Sánchez León, María Luisa; Jiménez Cortegana, Carlos; Silva Romeiro, Silvia; Garnacho Montero, Carmen; Cruz Merino, Luis de la; García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Sánchez Margalet, Víctor (Mdpi Ag, 2023)Breast cancer (BC) continues to be the most diagnosed tumor in women and a very heterogeneous disease both inter- and ...
-
Artículo
Dendritic cells: the yin and yang in disease progression
Jiménez Cortegana, Carlos; Palomares, Francisca; Alba Jiménez, Gonzalo; Santa-María Pérez, Consuelo; Cruz Merino, Luis de la; Sánchez Margalet, Víctor; López Enriquez, Soledad (Frontiers Media, 2024-01-04)Dendritic cells (DCs) are antigen presenting cells that link innate and adaptive immunity. DCs have been historically ...